Ann Neurol:语言功能磁共振成像在癫痫术前检测中的应用

2017-04-24 zhangfan MedSci原创

语言功能性磁共振成像是一种有效的无创语言功能区定位手段,对于癫痫切除术中防止关键语言区域意外损伤有重要作用

术前评估可以有效减少癫痫切除术中语言功能区损伤。手术前的语言评估的方法有两种,功能性磁共振成像(fMRI)和硬膜下电极植入皮层刺激(DCS)。研究人员近日将fMRI法的结果与DCS法进行比较,以优化并评估这种无创术前评估法。

研究中对19例耐药性癫痫患者进行术前评估。首先患者完成4项术前fMRI语言刺激测试,之后患者植入硬膜下电极,使用DCS进行语音功能区定位。对于每一种语言刺激,研究者确定DCS结果是否与fMRI结果相一致。

研究发现,对于至少有一种语言电刺激测试敏感的患者,听觉描述测试(fMRI语言刺激测试的一种)表现出最佳的灵敏度和特异性;对于语言电刺激测试不敏感的患者,fMRI是一种可靠的辨别语言功能区的方法。

研究认为,语言功能性磁共振成像是一种有效的无创语言功能区定位手段,对于癫痫切除术中防止关键语言区域意外损伤有重要作用。语言功能性磁共振成像还可以帮助引导硬膜下电极植入并缩小皮层电刺激的搜索范围。

原文出处:


本文系梅斯医学(MedSci)原创编译整理,转载需授权!

版权声明:
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料,版权均属于梅斯医学所有。非经授权,任何媒体、网站或个人不得转载,授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章,或“梅斯号”自媒体发布的文章,仅系出于传递更多信息之目的,本站仅负责审核内容合规,其内容不代表本站立场,本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系,我们将立即进行删除处理。
在此留言
评论区 (6)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1999901, encodeId=259e199990146, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Wed Mar 14 14:37:00 CST 2018, time=2018-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1954371, encodeId=c3bd19543e19e, content=<a href='/topic/show?id=955232931f1' target=_blank style='color:#2F92EE;'>#功能磁共振成像#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32931, encryptionId=955232931f1, topicName=功能磁共振成像)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Mon Sep 18 16:37:00 CST 2017, time=2017-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1341561, encodeId=769f1341561a8, content=<a href='/topic/show?id=24b8e37529a' target=_blank style='color:#2F92EE;'>#磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73752, encryptionId=24b8e37529a, topicName=磁共振)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=24a22500182, createdName=1696533704_45270454, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1418170, encodeId=c7ff14181e0b3, content=<a href='/topic/show?id=a4719180605' target=_blank style='color:#2F92EE;'>#语言#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91806, encryptionId=a4719180605, topicName=语言)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c16b3335392, createdName=yangjxjc, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1530800, encodeId=d18d1530800eb, content=<a href='/topic/show?id=afd49180951' target=_blank style='color:#2F92EE;'>#语言功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91809, encryptionId=afd49180951, topicName=语言功能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=507d12125901, createdName=w363522453, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1543392, encodeId=309215433923c, content=<a href='/topic/show?id=665632930d8' target=_blank style='color:#2F92EE;'>#功能磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32930, encryptionId=665632930d8, topicName=功能磁共振)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6cae13580069, createdName=1249884fm91暂无昵称, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=)]
    2018-03-14 yinhl1978
  2. [GetPortalCommentsPageByObjectIdResponse(id=1999901, encodeId=259e199990146, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Wed Mar 14 14:37:00 CST 2018, time=2018-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1954371, encodeId=c3bd19543e19e, content=<a href='/topic/show?id=955232931f1' target=_blank style='color:#2F92EE;'>#功能磁共振成像#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32931, encryptionId=955232931f1, topicName=功能磁共振成像)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Mon Sep 18 16:37:00 CST 2017, time=2017-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1341561, encodeId=769f1341561a8, content=<a href='/topic/show?id=24b8e37529a' target=_blank style='color:#2F92EE;'>#磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73752, encryptionId=24b8e37529a, topicName=磁共振)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=24a22500182, createdName=1696533704_45270454, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1418170, encodeId=c7ff14181e0b3, content=<a href='/topic/show?id=a4719180605' target=_blank style='color:#2F92EE;'>#语言#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91806, encryptionId=a4719180605, topicName=语言)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c16b3335392, createdName=yangjxjc, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1530800, encodeId=d18d1530800eb, content=<a href='/topic/show?id=afd49180951' target=_blank style='color:#2F92EE;'>#语言功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91809, encryptionId=afd49180951, topicName=语言功能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=507d12125901, createdName=w363522453, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1543392, encodeId=309215433923c, content=<a href='/topic/show?id=665632930d8' target=_blank style='color:#2F92EE;'>#功能磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32930, encryptionId=665632930d8, topicName=功能磁共振)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6cae13580069, createdName=1249884fm91暂无昵称, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=)]
  3. [GetPortalCommentsPageByObjectIdResponse(id=1999901, encodeId=259e199990146, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Wed Mar 14 14:37:00 CST 2018, time=2018-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1954371, encodeId=c3bd19543e19e, content=<a href='/topic/show?id=955232931f1' target=_blank style='color:#2F92EE;'>#功能磁共振成像#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32931, encryptionId=955232931f1, topicName=功能磁共振成像)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Mon Sep 18 16:37:00 CST 2017, time=2017-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1341561, encodeId=769f1341561a8, content=<a href='/topic/show?id=24b8e37529a' target=_blank style='color:#2F92EE;'>#磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73752, encryptionId=24b8e37529a, topicName=磁共振)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=24a22500182, createdName=1696533704_45270454, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1418170, encodeId=c7ff14181e0b3, content=<a href='/topic/show?id=a4719180605' target=_blank style='color:#2F92EE;'>#语言#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91806, encryptionId=a4719180605, topicName=语言)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c16b3335392, createdName=yangjxjc, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1530800, encodeId=d18d1530800eb, content=<a href='/topic/show?id=afd49180951' target=_blank style='color:#2F92EE;'>#语言功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91809, encryptionId=afd49180951, topicName=语言功能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=507d12125901, createdName=w363522453, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1543392, encodeId=309215433923c, content=<a href='/topic/show?id=665632930d8' target=_blank style='color:#2F92EE;'>#功能磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32930, encryptionId=665632930d8, topicName=功能磁共振)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6cae13580069, createdName=1249884fm91暂无昵称, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=)]
  4. [GetPortalCommentsPageByObjectIdResponse(id=1999901, encodeId=259e199990146, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Wed Mar 14 14:37:00 CST 2018, time=2018-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1954371, encodeId=c3bd19543e19e, content=<a href='/topic/show?id=955232931f1' target=_blank style='color:#2F92EE;'>#功能磁共振成像#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32931, encryptionId=955232931f1, topicName=功能磁共振成像)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Mon Sep 18 16:37:00 CST 2017, time=2017-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1341561, encodeId=769f1341561a8, content=<a href='/topic/show?id=24b8e37529a' target=_blank style='color:#2F92EE;'>#磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73752, encryptionId=24b8e37529a, topicName=磁共振)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=24a22500182, createdName=1696533704_45270454, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1418170, encodeId=c7ff14181e0b3, content=<a href='/topic/show?id=a4719180605' target=_blank style='color:#2F92EE;'>#语言#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91806, encryptionId=a4719180605, topicName=语言)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c16b3335392, createdName=yangjxjc, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1530800, encodeId=d18d1530800eb, content=<a href='/topic/show?id=afd49180951' target=_blank style='color:#2F92EE;'>#语言功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91809, encryptionId=afd49180951, topicName=语言功能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=507d12125901, createdName=w363522453, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1543392, encodeId=309215433923c, content=<a href='/topic/show?id=665632930d8' target=_blank style='color:#2F92EE;'>#功能磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32930, encryptionId=665632930d8, topicName=功能磁共振)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6cae13580069, createdName=1249884fm91暂无昵称, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=)]
    2017-04-26 yangjxjc
  5. [GetPortalCommentsPageByObjectIdResponse(id=1999901, encodeId=259e199990146, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Wed Mar 14 14:37:00 CST 2018, time=2018-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1954371, encodeId=c3bd19543e19e, content=<a href='/topic/show?id=955232931f1' target=_blank style='color:#2F92EE;'>#功能磁共振成像#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32931, encryptionId=955232931f1, topicName=功能磁共振成像)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Mon Sep 18 16:37:00 CST 2017, time=2017-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1341561, encodeId=769f1341561a8, content=<a href='/topic/show?id=24b8e37529a' target=_blank style='color:#2F92EE;'>#磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73752, encryptionId=24b8e37529a, topicName=磁共振)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=24a22500182, createdName=1696533704_45270454, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1418170, encodeId=c7ff14181e0b3, content=<a href='/topic/show?id=a4719180605' target=_blank style='color:#2F92EE;'>#语言#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91806, encryptionId=a4719180605, topicName=语言)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c16b3335392, createdName=yangjxjc, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1530800, encodeId=d18d1530800eb, content=<a href='/topic/show?id=afd49180951' target=_blank style='color:#2F92EE;'>#语言功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91809, encryptionId=afd49180951, topicName=语言功能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=507d12125901, createdName=w363522453, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1543392, encodeId=309215433923c, content=<a href='/topic/show?id=665632930d8' target=_blank style='color:#2F92EE;'>#功能磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32930, encryptionId=665632930d8, topicName=功能磁共振)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6cae13580069, createdName=1249884fm91暂无昵称, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=)]
  6. [GetPortalCommentsPageByObjectIdResponse(id=1999901, encodeId=259e199990146, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Wed Mar 14 14:37:00 CST 2018, time=2018-03-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1954371, encodeId=c3bd19543e19e, content=<a href='/topic/show?id=955232931f1' target=_blank style='color:#2F92EE;'>#功能磁共振成像#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32931, encryptionId=955232931f1, topicName=功能磁共振成像)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=55683, createdName=仁医06, createdTime=Mon Sep 18 16:37:00 CST 2017, time=2017-09-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1341561, encodeId=769f1341561a8, content=<a href='/topic/show?id=24b8e37529a' target=_blank style='color:#2F92EE;'>#磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=73752, encryptionId=24b8e37529a, topicName=磁共振)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=24a22500182, createdName=1696533704_45270454, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1418170, encodeId=c7ff14181e0b3, content=<a href='/topic/show?id=a4719180605' target=_blank style='color:#2F92EE;'>#语言#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91806, encryptionId=a4719180605, topicName=语言)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c16b3335392, createdName=yangjxjc, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1530800, encodeId=d18d1530800eb, content=<a href='/topic/show?id=afd49180951' target=_blank style='color:#2F92EE;'>#语言功能#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=91809, encryptionId=afd49180951, topicName=语言功能)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=507d12125901, createdName=w363522453, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1543392, encodeId=309215433923c, content=<a href='/topic/show?id=665632930d8' target=_blank style='color:#2F92EE;'>#功能磁共振#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=32930, encryptionId=665632930d8, topicName=功能磁共振)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=6cae13580069, createdName=1249884fm91暂无昵称, createdTime=Wed Apr 26 00:37:00 CST 2017, time=2017-04-26, status=1, ipAttribution=)]

相关资讯

JAMA Neurol:孕期超重会增加后代癫痫风险

儿童癫痫的发生率与母体超重或肥胖呈正相关关系

一文读懂:近期癫痫相关重磅研究

Neurelis公司最近宣布,NRL-1(地西泮鼻喷雾)获得FDA的快速审定资格,用于治疗伴有急性复发性或群集性癫痫发作的小儿、青少年和成年患者。NRL-1是专门为经选择的、难治性癫痫患者设计的,这些患者已经接受抗癫痫药物治疗,但需要间歇性使用地西泮来管理其群集性癫痫发作。2015年,FDA已经授予NRL-1治疗急性癫痫发作孤儿药资格。来自纽约大学Langone 综合癫痫中心Jacquelin

AM J HUM GENET:在OTUD6B的Biallelic突变体与引起智力障碍综合症与癫痫发作有关

泛素化是一种翻译后修饰,调节许多细胞过程,包括蛋白质降解,细胞内运输,细胞信号传导和蛋白质 - 蛋白质相互作用。颠换泛素化过程的泛素化酶(DUBs)是泛素系统的重要调节因子。OTUD6B编码了含有脱蛋白酶的亚类的卵巢肿瘤结构域(OTU)成员。

Neurology:IDH1突变型脑胶质瘤患者癫痫发作率高

,异柠檬酸脱氢酶1突变生成的D-2 -羟基类固醇可增加神经元的活性,会增加异柠檬酸脱氢酶1突变胶质瘤患者癫痫发病率

JAMA Neurol:儿童癫痫伴中央颞区棘波猝死病例

癫痫猝死是一个非常罕见的BECTS结果,临床医生在实际工作中应考虑到癫痫猝死可能性并采取相应决策

Nature:调节中脑腹侧盖区Cbln1基因治疗自闭症

调节中脑腹侧盖区Cbln1基因治疗自闭症