JACC:减肥手术可减少肥胖心衰患者的病程进展

2016-03-10 崔倩 译 MedSci原创

美国正在于肥胖和心脏衰竭(HF)这些流行病进行对抗。尽管研究已经表明了肥胖和HF发病率之间的关系,但很少有研究表明肥胖HF患者体重大幅度减少后的效果。这项研究调查了减肥手术是否与心衰发作率降低有关。研究人员使用加州,佛罗里达州和内布拉斯加基于人群的急诊科(ED)和住院样本进行了自身对照病例系列研究,参与者为接受减肥手术的肥胖HF患者。主要成果是从2005年到2011年因HF恶化到ED就诊或住院的情

美国正在与肥胖和心力衰竭(HF)这些流行病进行对抗。尽管研究已经表明了肥胖和HF发病率之间的关系,但很少有研究表明肥胖HF患者体重大幅度减少二者之间的关系。

这项研究调查了减肥手术是否与心衰发作率降低有关。

研究人员使用加州、佛罗里达州和内布拉斯加基于人群的急诊科(ED)和住院样本进行了自身对照病例系列研究,参与者为接受减肥手术的肥胖HF患者。主要成果是从2005年到2011年因HF恶化到ED就诊或住院的情况。研究人员使用条件Logistic回归比较了在连续12个月期间的结果事件发生率,将手术前13个月至24个作为基准期。

研究人员确定了524例接受减肥手术的心衰患者。在报告期内,16.2%的患者有一次因HF恶化到ED就诊或住院。在随后的手术前12个月期间该概率保持不变(15.3%;P=0.67)。在减肥手术后的第一个12个月期间,研究人员观察到一个非显著性降低的概率(12.0%,P=0.052)。但是该概率在随后的减肥手术后13至24个月显著降低(9.9%;调整后的比值比:0.57; P=0.003)。相比之下,在接受非减肥手术(即胆囊切除术,子宫切除术)的肥胖患者中HF恶化的概率没有显著降低。

该研究结果表明,减肥手术减少了肥胖HF患者因HF恶化的接受ED评估或住院率。

原始出处:

Yuichi J. Shimada,Yusuke Tsugawa,David F.M. Brown,et al.Bariatric Surgery and Emergency Department Visits and Hospitalizations for Heart Failure Exacerbation,JACC,2016.3.1

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    2016-11-03 hbwxf
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    2016-03-22 1de304d2m86(暂无匿称)

    学习了,???

    0

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  5. [GetPortalCommentsPageByObjectIdResponse(id=1853495, encodeId=e6821853495b9, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Thu Nov 03 16:16:00 CST 2016, time=2016-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72689, encodeId=55d7e2689af, content=学习了,???, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=44b91679772, createdName=1de304d2m86(暂无匿称), createdTime=Tue Mar 22 13:10:00 CST 2016, time=2016-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1325192, encodeId=37f813251927c, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Sat Mar 12 13:16:00 CST 2016, time=2016-03-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1373302, encodeId=e00b13e3302f7, content=<a href='/topic/show?id=2fd051939ab' target=_blank style='color:#2F92EE;'>#心衰患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51939, encryptionId=2fd051939ab, topicName=心衰患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=467c360, createdName=yuanming7, createdTime=Sat Mar 12 13:16:00 CST 2016, time=2016-03-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=68597, encodeId=13aa6859ef6, content=专业实用的《医学科研口袋书》,现免费送!书以现代流行病学为基石,汇聚了来自哈佛、康奈尔及国内知名高校的临床科研工作者的实战经验汇编而成,如:《如何进行Meta分析》《大牛是如何写论文综述的》等的精彩文章。 <br> 微信搜索"LinkLab",关注,并将"邮箱地址"发送公众号后台,即可领取!, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=57281667222, createdName=1de01b3fm10(暂无匿称), createdTime=Fri Mar 11 12:50:00 CST 2016, time=2016-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=68576, encodeId=2c37685e674, content=弄错了,手术吧肥胖君!, beContent=null, objectType=article, channel=null, level=null, likeNumber=172, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=014e108570, createdName=chenchuny, createdTime=Fri Mar 11 09:39:00 CST 2016, time=2016-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=68575, encodeId=88ac685e548, content=滚蛋吧我的门诊君, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=014e108570, createdName=chenchuny, createdTime=Fri Mar 11 09:38:00 CST 2016, time=2016-03-11, status=1, ipAttribution=)]
    2016-03-11 1de01b3fm10(暂无匿称)

    专业实用的《医学科研口袋书》,现免费送!书以现代流行病学为基石,汇聚了来自哈佛、康奈尔及国内知名高校的临床科研工作者的实战经验汇编而成,如:《如何进行Meta分析》《大牛是如何写论文综述的》等的精彩文章。
    微信搜索"LinkLab",关注,并将"邮箱地址"发送公众号后台,即可领取!

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1853495, encodeId=e6821853495b9, content=<a href='/topic/show?id=48351020537' target=_blank style='color:#2F92EE;'>#JACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10205, encryptionId=48351020537, topicName=JACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=55ce62, createdName=hbwxf, createdTime=Thu Nov 03 16:16:00 CST 2016, time=2016-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=72689, encodeId=55d7e2689af, content=学习了,???, beContent=null, objectType=article, channel=null, level=null, likeNumber=132, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=44b91679772, createdName=1de304d2m86(暂无匿称), createdTime=Tue Mar 22 13:10:00 CST 2016, time=2016-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1325192, encodeId=37f813251927c, content=<a href='/topic/show?id=96c71804b7' target=_blank style='color:#2F92EE;'>#ACC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1804, encryptionId=96c71804b7, topicName=ACC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1e452500029, createdName=12498568m50暂无昵称, createdTime=Sat Mar 12 13:16:00 CST 2016, time=2016-03-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1373302, encodeId=e00b13e3302f7, content=<a href='/topic/show?id=2fd051939ab' target=_blank style='color:#2F92EE;'>#心衰患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51939, encryptionId=2fd051939ab, topicName=心衰患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=467c360, createdName=yuanming7, createdTime=Sat Mar 12 13:16:00 CST 2016, time=2016-03-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=68597, encodeId=13aa6859ef6, content=专业实用的《医学科研口袋书》,现免费送!书以现代流行病学为基石,汇聚了来自哈佛、康奈尔及国内知名高校的临床科研工作者的实战经验汇编而成,如:《如何进行Meta分析》《大牛是如何写论文综述的》等的精彩文章。 <br> 微信搜索"LinkLab",关注,并将"邮箱地址"发送公众号后台,即可领取!, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=57281667222, createdName=1de01b3fm10(暂无匿称), createdTime=Fri Mar 11 12:50:00 CST 2016, time=2016-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=68576, encodeId=2c37685e674, content=弄错了,手术吧肥胖君!, beContent=null, objectType=article, channel=null, level=null, likeNumber=172, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=014e108570, createdName=chenchuny, createdTime=Fri Mar 11 09:39:00 CST 2016, time=2016-03-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=68575, encodeId=88ac685e548, content=滚蛋吧我的门诊君, beContent=null, objectType=article, channel=null, level=null, likeNumber=110, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=014e108570, createdName=chenchuny, createdTime=Fri Mar 11 09:38:00 CST 2016, time=2016-03-11, status=1, ipAttribution=)]
    2016-03-11 chenchuny

    弄错了,手术吧肥胖君!

    0

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    2016-03-11 chenchuny

    滚蛋吧我的门诊君

    0

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