EASL 2014:内镜套扎治疗胃窦血管扩张优于氩气刀

2014-04-23 佚名 dxy

胃窦血管扩张症以胃窦黏膜和黏膜下血管扩张为特征,可导致肝硬化患者反复出现上消化道出血。氩气刀电凝(APC)治疗胃窦血管扩张症安全有效,但须进行多次内镜治疗。近期研究发现,内镜套扎治疗胃窦血管扩张症亦有效,可替代氩气刀电凝,尤其是在难治性病例当中。 本随机试验旨在对比评估氩气刀与内镜套扎治疗胃窦血管扩张症的安全性及有效性。共纳入88名胃窦黏膜血管扩张症的肝硬化患者,随机分为套扎组和氩气刀组,进行2周

胃窦血管扩张症以胃窦黏膜和黏膜下血管扩张为特征,可导致肝硬化患者反复出现上消化道出血。氩气刀电凝(APC)治疗胃窦血管扩张症安全有效,但须进行多次内镜治疗。近期研究发现,内镜套扎治疗胃窦血管扩张症亦有效,可替代氩气刀电凝,尤其是在难治性病例当中。

本随机试验旨在对比评估氩气刀与内镜套扎治疗胃窦血管扩张症的安全性及有效性。共纳入88名胃窦黏膜血管扩张症的肝硬化患者,随机分为套扎组和氩气刀组,进行2周一次的内镜治疗,直到内镜下止血。随访6月,每月评估血红蛋白水平。

研究发现,套扎组中的13名患者和氩气刀组的9名患者在贲门周围发现类似病灶,为胃底黏膜血管扩张症表现。内镜套扎治疗可显著减少内镜治疗的次数,平均为2.98次,而氩气刀组为3.48次。

两组术后都可显著提升血红蛋白水平,但在提升的程度上有显著差异,套扎组输血量也显著少于氩气刀组。

在治疗肝硬化患者的胃窦血管扩张症和胃底血管扩张症时,内镜套扎治疗比氩气刀更安全有效,并可显著减少输血量。

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    2015-02-01 lsj637
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    2014-04-25 kord1983
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    2014-04-25 lq1771

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