Circulation:体力消耗,愤怒和情绪不安都会引发急性心肌梗死

2016-10-11 MedSci MedSci原创

据报道,体力消耗,愤怒和情绪不安会引发急性心肌梗死(AMI)。在INTERHEART研究中,研究人员探讨了剧烈的身体活动和愤怒或情绪不安与AMI的触发关联,以量化这些潜在触发因素在大型国际人群中的重要性。INTERHEART是一项第一次在52个国家中开展的AMI病例对照研究。该分析仅包括了AMI病例,并使用病例交叉法来估计在触发后1小时内发生的AMI的比值比。在12461例AMI患者中,在发病期(

据报道,体力消耗,愤怒和情绪不安会引发急性心肌梗死(AMI)。在INTERHEART研究中,研究人员探讨了剧烈的身体活动和愤怒或情绪不安与AMI的触发关联,以量化这些潜在触发因素在大型国际人群中的重要性。

INTERHEART是一项第一次在52个国家中开展的AMI病例对照研究。该分析仅包括了AMI病例,并使用病例交叉法来估计在触发后1小时内发生的AMI的比值比。

在12461例AMI患者中,在发病期(症状出现前1小时),13.6%的患者(n=1650)从事过体力活动,14.4%的患者(n=1752)出现生气或情绪不安。在发病期间体力活动增加了发生AMI的可能性(比值比,2.31; 99%置信区间[CI],1.96-2.72),人群归因风险度为7.7%(99%CI,6.3-8.8)。在发病期间愤怒或情绪不安也增加了发生AMI的可能性(比值比,2.44; 99%CI,2.06-2.89),人群归因风险度为8.5%(99%CI,7.0-9.6)。地理区域,心血管疾病史,心血管风险因素负担,心血管预防药物,或发生AMI的时间对该影响没有效应修饰作用。在发病期间体力活动和愤怒或情绪不安进一步增加了发生AMI的可能性(比值比,3.05; 99%CI,2.29-4.07; 相互作用P<0.001)。

在世界范围内,男性和女性中,所有的年龄段,剧烈体力活动和愤怒或情绪不安是发生第一次AMI的触发因素,并且没有显著的效应修饰。

原始出处:

Andrew Smyth, Martin O’Donnell, Pablo Lamelas,et al.Physical Activity and Anger or Emotional Upset as Triggers of Acute Myocardial Infarction,Circulation,2016.10.11


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  1. [GetPortalCommentsPageByObjectIdResponse(id=146735, encodeId=31ee146e35d9, content=急性心肌梗死与情绪,体力消耗密切相关,所以,学会调节, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K3j7ibEWPiarwpqibEYqqX9yVibV5uebib0O7hQSOPmqGrb5FfyDbLsLawnz7ShAb5ibtiayWgI5ClMTh5v/0, createdBy=a47c1614293, createdName=童小孩, createdTime=Wed Oct 12 12:56:32 CST 2016, time=2016-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=145115, encodeId=e3ce145115fb, content=继续关注!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160811/IMG57AC91915ACA64463.jpg, createdBy=9c351934462, createdName=知难而进, createdTime=Tue Oct 11 19:49:06 CST 2016, time=2016-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=145113, encodeId=bcd2145113b3, content=谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160811/IMG57AC91915ACA64463.jpg, createdBy=9c351934462, createdName=知难而进, createdTime=Tue Oct 11 19:49:00 CST 2016, time=2016-10-11, status=1, ipAttribution=)]
    2016-10-12 童小孩

    急性心肌梗死与情绪,体力消耗密切相关,所以,学会调节

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=146735, encodeId=31ee146e35d9, content=急性心肌梗死与情绪,体力消耗密切相关,所以,学会调节, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K3j7ibEWPiarwpqibEYqqX9yVibV5uebib0O7hQSOPmqGrb5FfyDbLsLawnz7ShAb5ibtiayWgI5ClMTh5v/0, createdBy=a47c1614293, createdName=童小孩, createdTime=Wed Oct 12 12:56:32 CST 2016, time=2016-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=145115, encodeId=e3ce145115fb, content=继续关注!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160811/IMG57AC91915ACA64463.jpg, createdBy=9c351934462, createdName=知难而进, createdTime=Tue Oct 11 19:49:06 CST 2016, time=2016-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=145113, encodeId=bcd2145113b3, content=谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160811/IMG57AC91915ACA64463.jpg, createdBy=9c351934462, createdName=知难而进, createdTime=Tue Oct 11 19:49:00 CST 2016, time=2016-10-11, status=1, ipAttribution=)]
    2016-10-11 知难而进

    继续关注!

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=146735, encodeId=31ee146e35d9, content=急性心肌梗死与情绪,体力消耗密切相关,所以,学会调节, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K3j7ibEWPiarwpqibEYqqX9yVibV5uebib0O7hQSOPmqGrb5FfyDbLsLawnz7ShAb5ibtiayWgI5ClMTh5v/0, createdBy=a47c1614293, createdName=童小孩, createdTime=Wed Oct 12 12:56:32 CST 2016, time=2016-10-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=145115, encodeId=e3ce145115fb, content=继续关注!, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160811/IMG57AC91915ACA64463.jpg, createdBy=9c351934462, createdName=知难而进, createdTime=Tue Oct 11 19:49:06 CST 2016, time=2016-10-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=145113, encodeId=bcd2145113b3, content=谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160811/IMG57AC91915ACA64463.jpg, createdBy=9c351934462, createdName=知难而进, createdTime=Tue Oct 11 19:49:00 CST 2016, time=2016-10-11, status=1, ipAttribution=)]
    2016-10-11 知难而进

    谢谢分享!

    0