2019年DDW:针对炎症性肠病的抗TNF治疗不会增加感染风险

2019-05-23 不详 网络

根据5月18日在DDW中发表的一项大型前瞻性多中心队列研究,针对炎症性肠病(IBD)的抗TNF治疗不会增加感染风险。

根据518日在DDW中发表的一项大型前瞻性多中心队列研究,针对炎症性肠病IBD)的抗TNF治疗不会增加感染风险。

西奈山伊坎医学院的Benjamin Lee Cohen博士解释说:TNF治疗在IBD中具有变革性,可提高缓解率。然而,这项治疗使得患者免疫功能受损,并且潜在的感染易感性被认为是一个重要的问题。为了研究抗TNF是否确实为腹腔内手术后感染的危险因素,Cohen博士及克罗恩病和结肠炎基金临床研究联盟的同事对正在接受治疗的955名患者进行了研究。总共有382名患者(40%)在手术后12周内接受了术前抗TNF暴露。单因素分析显示,抗TNF暴露组和无TNF暴露组的感染率无显著差异(分别为19.4%和20.2%,P=0.80),两组间手术部位感染率无差异(分别为12.3%和12.7%,P=0.92)。


原始出处:

http://www.firstwordpharma.com/node/1642713#axzz5okQFj1Sv

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    2019-09-28 mfx808
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    2019-05-25 snowpeakxu
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    2019-05-25 aids214
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    2019-05-23 orangesking

    0

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