慢性疲劳综合征动物模型研究申请书（国家自然科学基金）

2009-02-23 MedSci原创 MedSci原创

这是一份08年的国家自然基金标书据说初审专家给出了2A+1B的较高评价虽然在最后PK阶段被Pass了但专家还是给予了很高赞誉赶快下载看看吧记得给予评价哟摘要：作为亚健康重要组成部分的慢性疲劳综合征（CFS）将成为21世纪影响人类健康的严重问题之一，开展对CFS的系统化研究具有重要的现实意义。由于缺乏公认的CFS实验动物模型，导致CFS的基础研究以及防治研究未见突破性进展。以往的研究主要通过注射病毒

这是一份08年的国家自然基金标书据说初审专家给出了2A+1B的较高评价虽然在最后PK阶段被Pass了但专家还是给予了很高赞誉赶快下载看看吧记得给予评价哟摘要：作为亚健康重要组成部分的慢性疲劳综合征（CFS）将成为21世纪影响人类健康的严重问题之一，开展对CFS的系统化研究具有重要的现实意义。由于缺乏公认的CFS实验动物模型，导致CFS的基础研究以及防治研究未见突破性进展。以往的研究主要通过注射病毒、慢性束缚的方法制作慢性疲劳动物模型，与人体CFS发病的多因性有较大差距，且检测指标单一，不能满足CFS系统研究的需要。基于目前慢性疲劳动物模型研究的不成熟，本课题从病因学方面入手，不仅使动物慢性疲劳运动，而且干扰其正常睡眠，扰乱生理节律，从而使动物模型更接近于临床实际，同时系统检测CFS大鼠在免疫系统、神经系统功能异常和行为异常改变方面的多项指标。为进一步研究CFS的发病机制、防治方法提供符合临床实际的、标准的、可重复的、可控易行的实验动物模型，推动CFS研究的发展。慢性疲劳综合征动物模型研究申请书（国家自然科学基金）.doc

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2011-12-20 liqing2012

good

107 0
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2011-01-29 andyyan0903

初审专家给出了2A+1B的较高评价，为何还没被PASS了呢？值得深思啊！

117 0
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2010-03-31 wusea131

不错，谢谢

90 0
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2009-11-26 wxr2009

good

104 0
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2009-04-12 nian.wang1991

#慢性疲劳综合征#

36 0
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2009-11-25 lujian

#科学基金#

35 0
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2009-10-18 caoshehua

good

116 0
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2009-04-19 ms5187542471278033

#申请书#

37 0
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2009-07-17 zylxndx

内容不完整，只有前面一点内容

84 0
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2009-07-04 85281372

assssa

82 0

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