Eur Heart J:射频消融适用于持续单一型室性心动过速治疗

2014-02-18 高晓方 译 医学论坛网

欧洲一项研究表明,在持续单一型室性心动过速(SMVT)患者中,未置入ICD射频消融治疗所引起的心律失常性死亡发生率极低,并且复发通常为非致命性。论文于2月16日在线发表于《欧洲心脏杂志》(Eur Heart J)。【原文下载】 此项研究共纳入166例左室射血分数(LVEF)>30%且伴有结构性心脏病的耐受良好SMVT患者;受试者均在未置入ICD的情况下接受射频消融治疗。受试者平均年龄为62

欧洲一项研究表明,在持续单一型室性心动过速(SMVT)患者中,未置入ICD射频消融治疗所引起的心律失常性死亡发生率极低,并且复发通常为非致命性。论文于2月16日在线发表于《欧洲心脏杂志》(Eur Heart J)。【原文下载】

此项研究共纳入166例左室射血分数(LVEF)>30%且伴有结构性心脏病的耐受良好SMVT患者;受试者均在未置入ICD的情况下接受射频消融治疗。受试者平均年龄为62 ± 15岁,平均LVEF为50 ± 10%,男性占84%。伴有缺血性心脏病、非缺血性心肌病和心律失常性右心室心肌病的患者分别占55%、19%和12%。378例在同期置入ICD的相似患者作为对照组。

结果显示,平均随访32 ± 27个月期间全因死亡率为12%(20例)。非心血管病因死亡、非心律失常性心血管病因死亡和猝死患者分别为8、8和4例。对照组全因死亡率为12%。在中位随访5个月时27例(16%)患者出现非致命性复发,20例(12%)患者需要置入ICD,其中4例死亡。

原始出处:

Philippe Maury1,*, Francesca Baratto2, Katja Zeppenfeld3, George Klein4, Etienne Delacretaz5, Frederic Sacher6, Etienne Pruvot7, Francois Brigadeau8, Anne Rollin1, Marius Andronache9, Giuseppe Maccabelli2, Marcin Gawrysiak3, Roman Brenner5, Andrei Forclaz6, Jürg Schlaepfer7, Dominique Lacroix8, Alexandre Duparc1, Pierre Mondoly1, Frederic Bouisset1, Marc Delay1, Meleze Hocini6, Nicolas Derval6, Nicolas Sadoul9, Isabelle Magnin-Poull9, Didier Klug8, Michel Haïssaguerre6, Pierre Jaïs6, Paolo Della Bella2 and Christian De Chillou9.Radio-frequency ablation as primary management of well-tolerated sustained monomorphic ventricular tachycardia in patients with structural heart disease and left ventricular ejection fraction over 30%.Eur Heart J February 16, 2014.doi: 10.1093/eurheartj/ehu040【原文下载】

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    2014-02-20 zhaojie88
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