Lancet:全球房颤患者诊疗大比拼:中国卒中发生率竟与非洲比肩,原来是这两件事儿未做好

2016-12-08 中国循环杂志 中国循环杂志

Lancet杂志近期公布了RELY房颤注册研究全球47个国家的急诊房颤注册结果。该研究共登记约1.5例房颤患者,并随访了1年,其中4%的患者发生了卒中。中国房颤患者1年卒中发生率7%,仅次于非洲(8%)。印度最低(1%),北美3%。 中国有服用抗凝药物指证的房颤患者中,有70%未应用抗凝药物。在47个国家中最差。但作者也表示,除抗凝药物应用不足之外,中国和非洲的卒中发生率高,也与高血压控

Lancet杂志近期公布了RELY房颤注册研究全球47个国家的急诊房颤注册结果。该研究共登记约1.5例房颤患者,并随访了1年,其中4%的患者发生了卒中


中国房颤患者1年卒中发生率7%,仅次于非洲(8%)。印度最低(1%),北美3%。 

中国有服用抗凝药物指证的房颤患者中,有70%未应用抗凝药物。在47个国家中最差。

但作者也表示,除抗凝药物应用不足之外,中国和非洲的卒中发生率高,也与高血压控制不佳有关系。中国有34%的患者高血压未控制。 

中国房颤患者在1年时,有14%死亡,有17%因心衰住院,有1%发生其他部位的栓塞。 

心衰是全球房颤患者最常见的死亡原因,30%的死亡原因是心衰,8%的死因是卒中。 

研究还发现,与因房颤就诊的患者相比,因其他疾病就诊但伴有房颤的患者死亡、卒中或因心衰住院的风险增加2倍。但临床试验往往排除了这些患者。 

该项目的中国区负责人是阜外医院的朱俊教授。RELY房颤注册研究由勃林格公司资助。 

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    2017-05-09 howi
  3. [GetPortalCommentsPageByObjectIdResponse(id=1826334, encodeId=ac65182633457, content=<a href='/topic/show?id=e5283e89970' target=_blank style='color:#2F92EE;'>#发生率#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37899, encryptionId=e5283e89970, topicName=发生率)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30bd35, createdName=一叶知秋, createdTime=Sat Jan 07 19:59:00 CST 2017, time=2017-01-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1828703, encodeId=133d1828e039d, content=<a href='/topic/show?id=1b6210686b2' target=_blank style='color:#2F92EE;'>#Lancet#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=10686, encryptionId=1b6210686b2, topicName=Lancet)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3f0227, createdName=howi, createdTime=Tue May 09 14:59:00 CST 2017, time=2017-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=163808, encodeId=0823163808e4, content=很好,不错,以后会多学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=83, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzUn81b5CF5ibVPib8jWI92iciaxmqGHlwruOnK4SVZykd4iahqo1hicklIibyZoxm55X7EM8BW9eX1h1hQ2/0, createdBy=8aa81937526, createdName=李东泽, createdTime=Sun Dec 18 15:24:50 CST 2016, time=2016-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=163196, encodeId=7f6816319617, content=最近关于卒中的文章好多, beContent=null, objectType=article, channel=null, level=null, likeNumber=79, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=29ab1719082, createdName=MyQueen, createdTime=Fri Dec 16 08:37:13 CST 2016, time=2016-12-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1614331, encodeId=77b31614331cc, content=<a href='/topic/show?id=64f95426122' target=_blank style='color:#2F92EE;'>#房颤患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=54261, encryptionId=64f95426122, topicName=房颤患者)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Sat Dec 10 04:59:00 CST 2016, time=2016-12-10, status=1, ipAttribution=)]
    2016-12-18 李东泽

    很好,不错,以后会多学习

    0

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    2016-12-16 MyQueen

    最近关于卒中的文章好多

    0

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由此可见,对于接受PCI并置入支架的房颤患者,运用小剂量利伐沙班加上P2Y12抑制剂12个月或极低剂量利伐沙班加DAPT治疗1、6或12个月比用维生素K拮抗剂加DAPT治疗1、6或12个月的标准治疗发生临床大出血几率更低。三组的疗效相似,即便观察到置信区间较广,会减少关于疗效任何结论的可靠性。