Diabetes Care:饮用咖啡可降低2型糖尿病风险

2014-04-29 desperado-c 丁香园

以前的荟萃分析表明咖啡摄入量与2型糖尿病风险呈负相关。然而,从那以后又有新的研究比较含咖啡因咖啡和无咖啡因咖啡与2型糖尿病风险关系,因此,需要对饮用咖啡与2型糖尿病风险的荟萃分析进行更新。 为此,来自美国哈佛大学公共卫生学院营养科的Frank B Hu教授及其团队进行一项研究,对已发表的比较饮用咖啡与2型糖尿病风险关系研究进行荟萃分析。该研究结果发表在2014年02月的Diabetes care

以前的荟萃分析表明咖啡摄入量与2型糖尿病风险呈负相关。然而,从那以后又有新的研究比较含咖啡因咖啡和无咖啡因咖啡与2型糖尿病风险关系,因此,需要对饮用咖啡与2型糖尿病风险的荟萃分析进行更新。

为此,来自美国哈佛大学公共卫生学院营养科的Frank B Hu教授及其团队进行一项研究,对已发表的比较饮用咖啡与2型糖尿病风险关系研究进行荟萃分析。该研究结果发表在2014年02月的Diabetes care杂志上。

该研究中,Frank B Hu教授等系统检索了PubMed和Embase数据库,选择评估饮用咖啡与2型糖尿病风险关系的队列研究或巢式病例对照研究,检索期限为1966年至2013年02月。使用限制性三次样条随机效应模型比较咖啡摄入量与2型糖尿病分析的关系。

最终,共有28项前瞻性研究入选,包括1109272例受试者和45335例2型糖尿病病例。随访周期从10月到20年不等。与从未饮用咖啡或极少饮用咖啡的受试者相比,每天饮用咖啡1到6杯的受试者糖尿病相对风险为0.92、0.85、0.79、0.75、0.71和0.67。每天多饮用一杯含咖啡因咖啡和无咖啡因咖啡,糖尿病相对风险分别为0.91和0.94。

该研究提示,饮用咖啡与2型糖尿病风险呈负相关,且两者存在剂量反应关系。不论是含咖啡因咖啡,还是无咖啡因咖啡都可降低糖尿病风险。

原始出处:


Ding M1, Bhupathiraju SN, Chen M, van Dam RM, Hu FB.Caffeinated and decaffeinated coffee consumption and risk of type 2 diabetes: a systematic review and a dose-response meta-analysis.Diabetes Care. 2014 Feb;37(2):569-86. doi: 10.2337/dc13-1203.

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    2014-09-17 智智灵药
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