Design of Xenopus GLP-1-Based Long-Acting Dual GLP-1/Y2 Receptor Agonists

Yang, QM; Tang, WZ; Sun, LD; Yan, ZM; Tang, CL; Yuan, YL; Zhou, H; Zhou, F; Zhou, SY; Wu, QQ; Song, P; Fang, T; Xu, RL; Han, J; Jiang, N

Jiang, N (通讯作者)，Guangxi Med Univ Canc Hosp, Dept Pharm, Nanning 530021, Peoples R China.;Han, J (通讯作者)，Jiangsu Normal Univ, Sch Chem & Mat Sci, Xuzhou 221116, Peoples R China.

JOURNAL OF MEDICINAL CHEMISTRY, 2022; 65 (20): 14201

Abstract

symbolscript GLP-1 receptor (GLP-1R) and neuropeptide Y2 receptor (Y2R) dual agonists have shown great potential to treat obesity and type 2 diabetes ......

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