Role of angiopoietin-like 3 (ANGPTL3) in regulating plasma level of low-density lipoprotein cholesterol

Xu, YX; Redon, V; Yu, HJ; Querbes, W; Pirruccello, J; Liebow, A; Deik, A; Trindade, K; Wang, X; Musunuru, K; Clish, CB; Cowan, C; Fizgerald, K; Rader, D; Kathiresan, S

Kathiresan, S (reprint author), Massachusetts Gen Hosp, Ctr Genom Med, Simches 5-830,185 Cambridge St, Boston, MA 02114 USA.; Kathiresan, S (reprint author), Massachusetts Gen Hosp, Cardiovasc Res Ctr, Simches 5-830,185 Cambridge St, Boston, MA 02114 USA.

ATHEROSCLEROSIS, 2018; 268 (): 196

Abstract

Background and aims: Angiopoietin-like 3 (ANGPTL3) has emerged as a key regulator of lipoprotein metabolism in humans. Homozygous loss of ANGPTL3 func......

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