Compensatory changes in CYP expression in three different toxicology mouse models: CAR-null, Cyp3a-null, and Cyp2b9/10/13-null mice

Kumar, R; Mota, LC; Litoff, EJ; Rooney, JP; Boswell, WT; Courter, E; Henderson, CM; Hernandez, JP; Corton, JC; Moore, DD; Baldwin, WS

Baldwin, WS (reprint author), Clemson Univ, Biol Sci, Clemson, SC 29634 USA.; Baldwin, WS (reprint author), Clemson Univ, Environm Toxicol, Pendleton, SC 29670 USA.

PLOS ONE, 2017; 12 (3):

Abstract

Targeted mutant models are common in mechanistic toxicology experiments investigating the absorption, metabolism, distribution, or elimination (ADME) ......

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