Salt Sensing by Serum/Glucocorticoid-Regulated Kinase 1 Promotes Th17-like Inflammatory Adaptation of Foxp(3+) Regulatory T Cells

Yang, YJH; Istomine, R; Alvarez, F; Al-Aubodah, TA; Shi, XQ; Takano, T; Thornton, AM; Shevach, EM; Zhang, J; Piccirillo, CA

Piccirillo, CA (corresponding author), McGill Univ, Dept Microbiol & Immunol, Montreal, PQ H3A 2B4, Canada.; Piccirillo, CA (corresponding author), McGill Univ, Hlth Ctr, Res Inst, Ctr Translat Biol,Program Infect Dis & Immunol Gl, Montreal, PQ H4A 3J1, Canada.; Piccirillo, CA (corresponding author), CETI, Montreal, PQ H4A 3J1, Canada.; Piccirillo, CA (corresponding author), McGill Univ, Div Expt Med, Dept Med, Montreal, PQ H4A 3J1, Canada.

CELL REPORTS, 2020; 30 (5): 1515

Abstract

Regulatory T (Treg) cells integrate diverse environmental signals to modulate their function for optimal suppression. Translational regulation represe......

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