In silico prediction of ARB resistance: A first step in creating personalized ARB therapy

Anderson, SD; Tabassum, A; Yeon, JK; Sharma, G; Santos, P; Soong, TH; Thu, YW; Nies, I; Kurita, T; Chandler, A; Alsamarah, A; Kanassatega, RS; Luo, YL; Botello-Smith, WM; Andresen, BT

Luo, YL; Botello-Smith, WM; Andresen, BT (corresponding author), Western Univ Hlth Sci, Coll Pharm, Dept Pharmaceut Sci, Pomona, CA 91766 USA.

PLOS COMPUTATIONAL BIOLOGY, 2020; 16 (11):

Abstract

Angiotensin II type 1 receptor (AT(1)R) blockers (ARBs) are among the most prescribed drugs. However, ARB effectiveness varies widely, which may be du......

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