Lupus IgG deposition causes arthritis but inhibits bone destruction through competitive occupation of Fc gamma RI and reduced RANKL signalling

Qiao, W; Ding, HM; Zuo, YY; Jiang, LJ; Zhou, JY; Han, XX; Yu, LK; Du, R; Hedrich, CM; Deng, GM

Deng, GM (corresponding author), Huazhong Univ Sci & Technol, Tongji Med Coll, Union Hosp, Dept Rheumatol, Wuhan, Peoples R China.

CLINICAL & TRANSLATIONAL IMMUNOLOGY, 2020; 9 (9):

Abstract

Objectives. Bone destruction is a remarkable feature of inflammatory arthritis. It remains unknown why arthritis associated with the systemic autoimmu......

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