Preventive DNA vaccination against CEA-expressing tumors with anti-idiotypic scFv6.C4 DNA in CEA-expressing transgenic mice

Denapoli, PMA; Zanetti, BF; dos Santos, AA; de Moraes, JZ; Han, SW

Han, SW (reprint author), Univ Fed Sao Paulo, Res Ctr Gene Therapy, Sao Paulo, SP, Brazil.; Han, SW (reprint author), Univ Fed Sao Paulo, Dept Biophys, BR-04044010 Sao Paulo, SP, Brazil.

CANCER IMMUNOLOGY IMMUNOTHERAPY, 2017; 66 (3): 333

Abstract

Carcinoembryonic antigen (CEA) is expressed during embryonic life and in low level during adult life. Consequently, the CEA is recognized by the immun......

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