Early goal-directed and lactate-guided therapy in adult patients with severe sepsis and septic shock: a meta-analysis of randomized controlled trials

Ding, XF; Yang, ZY; Xu, ZT; Li, LF; Yuan, B; Guo, LN; Wang, LX; Zhu, X; Sun, TW

Sun, TW (reprint author), Zhengzhou Univ, Gen ICU, Affiliated Hosp 1, Zhengzhou 450052, Henan, Peoples R China.; Sun, TW (reprint author), Henan Key Lab Crit Care Med, Zhengzhou 450052, Henan, Peoples R China.; Zhu, X (reprint author), Peking Univ, Dept C

JOURNAL OF TRANSLATIONAL MEDICINE, 2018; 16 ():

Abstract

Background: The ProCESS, ARISE, and ProMISe trials have failed to show that early goal-directed therapy (EGDT) reduces mortality in patients with seve......

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