Immunogenicity and skin clearance recapture in clinical studies of brodalumab

Bagel, J; Lebwohl, M; Israel, RJ; Jacobson, A

Bagel, J (corresponding author), Psoriasis Treatment Ctr Cent New Jersey, 59 One Mile Rd Extens, East Windsor, NJ 08520 USA.

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2020; 82 (2): 344

Abstract

Background: Antidrug antibodies (ADAs) may change pharmacokinetic or pharmacodynamic profiles of biologic therapies, potentially decreasing efficacy. ......

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