The molecular basis of pyrazinamide activity on Mycobacterium tuberculosis PanD

Sun, QG; Li, XJ; Perez, LM; Shi, WL; Zhang, Y; Sacchettini, JC

Sacchettini, JC (corresponding author), Texas A&M Univ, Dept Biochem & Biophys, College Stn, TX 77843 USA.

NATURE COMMUNICATIONS, 2020; 11 (1):

Abstract

Pyrazinamide has been a mainstay in the multidrug regimens used to treat tuberculosis. It is active against the persistent, non-replicating mycobacter......

Full Text Link