期刊： LIFE SCIENCE ALLIANCE, 2022; 6 (1)
To understand the pathogenesis of acute lung injury (ALI), we focused on circEXOC5, a significantly up-regulated circular RNA in ALI. Using the in viv......
期刊： LIFE SCIENCE ALLIANCE, 2022; 5 (7)
Telomeres consist of highly conserved simple tandem telomeric repeat motif (TRM): (TTAGG)n in arthropods, (TTAGGG)n in vertebrates, and (TTTAGGG)n in ......
期刊： LIFE SCIENCE ALLIANCE, 2022; 5 (10)
Epithelial-mesenchymal transition (EMT) has fundamental roles in various biological processes. However, there are still questions pending in this fast......
期刊： LIFE SCIENCE ALLIANCE, 2022; 6 (1)
Understanding the molecular mechanism underlying the rampant mutation of SARS-CoV-2 would help us control the COVID-19 pandemic. The APOBEC-mediated C......
期刊： LIFE SCIENCE ALLIANCE, 2022; 6 (2)
Whereas the role of the nucleotide-binding oligomerization domain, leucine-rich repeat and pyrin domain-containing protein (NLRP) 3 pathway in innate ......
期刊： LIFE SCIENCE ALLIANCE, 2022; 6 (3)
Baroreceptors are nerve endings located in the adventitia of the carotid sinus and aortic arch. They act as a mechanoelectrical transducer that can se......
期刊： LIFE SCIENCE ALLIANCE, 2022; 5 (8)
Fundamental to viral biology is identification and annotation of viral genes and their function. Determining the level of coronavirus gene expression ......
期刊： LIFE SCIENCE ALLIANCE, 2022; 5 (9)
Deleterious variants in DNA damage repair (DDR) system can cause genome instability and increase cancer risk. In this study, we analyzed the deleterio......
期刊： LIFE SCIENCE ALLIANCE, 2022; 6 (2)
Nonalcoholic fatty liver disease (NAFLD) is prevalent worldwide; about 25% of NAFLD silently progress into steatohepatitis, in which some of them may ......
期刊： LIFE SCIENCE ALLIANCE, 2022; 5 (1)
Single-domain antibody (sdAb) holds the promising strategies for diverse research and translational applications. Here, we describe a method for the a......
期刊： LIFE SCIENCE ALLIANCE, 2022; 5 (8)
Next-generation sequencing (NGS) promises to revolutionize precision medicine, but the existing sequencing technologies are limited in accuracy. To ov......
期刊： LIFE SCIENCE ALLIANCE, 2022; 5 (11)
Bombesin receptor-activated protein (BRAP) was found to express in the interstitial cells of human fibrotic lungs with unknown function. Its homologou......
期刊： LIFE SCIENCE ALLIANCE, 2021; 4 (7)
A purification protocol was developed to identify and analyze the component proteins of a postsynaptic density (PSD) lattice, a core structure of the ......
期刊： LIFE SCIENCE ALLIANCE, 2021; 4 (5)
Disseminated candidiasis remains as the most common hospital-acquired bloodstream fungal infection with up to 40% mortality rate despite the advanceme......
期刊： LIFE SCIENCE ALLIANCE, 2021; 4 (6)
In the last decade, transcription activator-like effector nucleases and CRISPR-based genome engineering have revolutionized our approach to biology. B......
