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A Beam Projection-Based Modified Gamma Analysis Scheme for Clinically Interpretable Pre-Treatment Dose Verification

期刊: DOSE-RESPONSE, 2021; 19 (2)

Purpose: To investigate a novel gamma analysis system for dose verification results in terms of clinical significance. Methods and Materials: The modi......

Genome-Wide Identification of Autophagy Prognostic Signature in Pancreatic Cancer

期刊: DOSE-RESPONSE, 2021; 19 (2)

Background: Autophagy plays a vital role in cancer development. However, there is currently no comprehensive study regarding the effects of autophagy-......

Preliminary Study on the Effect of 4DCT-Ventilation-Weighted Dose on the Radiation Induced Pneumonia Probability (RIPP)

期刊: DOSE-RESPONSE, 2021; 19 (3)

Purpose: The purpose of the present study was to evaluate the feasibility of using 4-dimensional computed tomography (4DCT)-ventilation-weighted dose ......

Celecoxib Alleviates Radiation-Induced Brain Injury in Rats by Maintaining the Integrity of Blood-Brain Barrier

期刊: DOSE-RESPONSE, 2021; 19 (2)

The underlying mechanisms of radiation-induced brain injury are poorly understood, although COX-2 inhibitors have been shown to reduce brain injury af......

Hepatoprotective Effects of Heracleum candicans Against Carbon Tetrachloride-Induced Acute Liver Injury in Rats

期刊: DOSE-RESPONSE, 2021; 19 (3)

Purpose: To determine the hepatoprotective mechanisms of Heracleum candicans in rats with acute liver injury induced by carbon tetrachloride (CCl4). M......

Diallyl Disulfide Attenuates Ionizing Radiation-Induced Migration and Invasion by Suppressing Nrf2 Signaling in Non-small-Cell Lung Cancer

期刊: DOSE-RESPONSE, 2021; 19 (3)

Non-small-cell lung cancer (NSCLC) is the leading cause of cancer-associated deaths. Radiotherapy remains the primary treatment method for NSCLC. Desp......

A Preliminary Study of Personalized Head CT Scan in Pediatric Patients

期刊: DOSE-RESPONSE, 2021; 19 (1)

Objectives: In the present study, we introduced a practical approach to quantify organ-specific radiation doses and investigated whether low-dose head......

Study on Caenorhabditis Elegans as a Combined Model of Microdosimetry and Biology

期刊: DOSE-RESPONSE, 2021; 19 (1)

Microdosimetry is a tool for the investigation of microscopic energy deposition of ionizing radiation. This work used Caenorhabditis elegans as a mode......

China: The New Powerhouse of Hormesis Research?

期刊: DOSE-RESPONSE, 2021; 19 (1)

More than one third of the worldwide hormesis research has been produced at institutions in the United States (US). Although the US ranked first in te......

Mesenchymal Stem Cell-Conditioned Medium Protects Hippocampal Neurons From Radiation Damage by Suppressing Oxidative Stress and Apoptosis

期刊: DOSE-RESPONSE, 2021; 19 (1)

Objective: To investigate the effects of mesenchymal stem cell-conditioned medium (MSC-CM) on radiation-induced oxidative stress, survival and apoptos......

MiRNA-873-5p Acts as a Potential Novel Biomarker and Promotes Cervical Cancer Progression by Regulating ZEB1 via Notch Signaling Pathway

期刊: DOSE-RESPONSE, 2021; 19 (1)

Objective: Our group aimed to investigate the expression pattern of miRNA-873-5p in cervical cancer (CC) patients and its association with CC progress......

Moscatilin Suppresses the Breast Cancer Both In Vitro and In Vivo by Inhibiting HDAC3

期刊: DOSE-RESPONSE, 2021; 19 (1)

Moscatilin, a natural compound isolated from the orchid Dendrobium moscatum, has multiple pharmacological actions. The present study investigated the ......

Hormesis Shifts the No-Observed-Adverse-Effect Level (NOAEL)

期刊: DOSE-RESPONSE, 2021; 19 (1)

Data from recent dose-response toxicological studies suggest that the no-observed-adverse-effect-level (NOAEL) may depend upon whether hormesis is pre......

A DNA Damage-Repair Dynamic Model for HRS/IRR Effects of C.elegans Induced by Neutron Irradiation

期刊: DOSE-RESPONSE, 2021; 19 (1)

Neutron irradiation which could trigger severe biological effects, is being applied in nuclear plants, radiotherapy, and aerospace gradually. Low dose......

Anti-Oxidative and Immuno-Protective Effect of Camel Milk on Radiation-Induced Intestinal Injury in C57BL/6 J Mice

期刊: DOSE-RESPONSE, 2021; 19 (1)

Purpose: The main objective is to investigate the protective effect of camel milk (CM) on radiation-induced intestinal injury. Methods: The C57BL/6 J ......

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