期刊： PHARMACOGENOMICS JOURNAL, 2022; 22 (2)
We aim to develop a formula based on single nucleotide polymorphisms (SNPs) to predict whether the propofol target-controlled infusion (TCI) concentra......
期刊： PHARMACOGENOMICS JOURNAL, ; ()
Background Filamin A and filamin B were involved in vascular development and remodeling. Herein, it is important to explore the associations of FLNA a......
期刊： PHARMACOGENOMICS JOURNAL, ; ()
Multiple myeloma (MM) is a malignancy of terminally differentiated plasma cells and does not have sufficient prognostic indicators. Interferon gamma i......
期刊： PHARMACOGENOMICS JOURNAL, ; ()
We compared a standard antihypertensive losartan treatment with a pharmacogenomics-guided rostafuroxin treatment in never-treated Caucasian and Chines......
期刊： PHARMACOGENOMICS JOURNAL, ; ()
The aim of this study was to identify novel genetic variants affecting tacrolimus trough blood concentrations. We analyzed the association between 58 ......
期刊： PHARMACOGENOMICS JOURNAL, 2020; 20 (6)
Genetic variations in DNA base excision repair (BER) genes may affect tumor sensitivity to chemotherapy and radiotherapy. Thus, we investigated the ef......
期刊： PHARMACOGENOMICS JOURNAL, 2020; 20 (6)
Bupropion is hydroxylated to its primary active metabolite hydroxybupropion by cytochrome P450 enzyme CYP2B6. In vitro data suggest the existence of a......
期刊： PHARMACOGENOMICS JOURNAL, 2020; 20 (3)
Tanshinone, a widely used Chinese patent medicine, has been confirmed to have various kinds of pharmacological effects although frequently causing cut......
期刊： PHARMACOGENOMICS JOURNAL, 2020; 20 (3)
Although numerous genetic studies have reported the link between Val66Met in BDNF gene with smoking, the findings remain controversial, mainly due to ......
期刊： PHARMACOGENOMICS JOURNAL, 2020; 20 (4)
The prognosis role of CCT3 in MM and the possible pathways it involved were studied in our research. By analyzing ten independent datasets (including ......
期刊： PHARMACOGENOMICS JOURNAL, 2020; 20 (4)
Few studies have investigated the correlation between pharmacogenomics and tacrolimus pharmacokinetics in patients with nephrotic syndrome (NS). This ......
期刊： PHARMACOGENOMICS JOURNAL, 2020; 20 (4)
Acute myeloid leukemia (AML) is a malignant disease of myeloid hematopoietic stem or progenitor cells characterized by abnormal proliferation of prima......
期刊： PHARMACOGENOMICS JOURNAL, 2020; 20 (1)
Cytochrome P450 2D6 (CYP2D6) and endothelial nitric oxide synthase (eNOS) are important in the cardiovascular disease susceptibility and drug response......
期刊： PHARMACOGENOMICS JOURNAL, 2020; 20 (1)
H1 nonsedating antihistamines, such as desloratadine, are first-line treatment options for chronic spontaneous urticaria (CSU). However, desloratadine......
期刊： PHARMACOGENOMICS JOURNAL, 2020; 20 (5)
Drug-induced liver injury (DILI) is a life-threatening, adverse reaction to certain drugs. The onset and extent of DILI can vary drastically in differ......
