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PAQR3 inhibits proliferation and aggravates ferroptosis in acute lymphoblastic leukemia through modulation Nrf2 stability

期刊: IMMUNITY INFLAMMATION AND DISEASE, 2021; 9 (3)

Introduction Acute lymphoblastic leukemia (ALL) is a usual hematological tumor, which was featured by malignant proliferation of lymphoid progenitor c......

Cyclin-dependent kinase 1 shows to be a potential genetic target for chemical cystitis

期刊: IMMUNITY INFLAMMATION AND DISEASE, 2021; 9 (3)

Background: In the present study, we aimed to explore whether common genetic targets or signaling pathways existed in chemical cystitis. Methods: Gene......

Association between neutrophils and renal impairment of rheumatoid arthritis: A retrospective cross-sectional study

期刊: IMMUNITY INFLAMMATION AND DISEASE, 2021; 9 (3)

Objective: Previous studies have shown that increased neutrophils, as a manifestation of oxidative stress, may be involved in the progression of kidne......

Nasal nitric oxide testing for allergic rhinitis patients: Systematic review and meta-analysis

期刊: IMMUNITY INFLAMMATION AND DISEASE, 2021; 9 (3)

Background: Nasal nitric oxide (nNO) levels in allergic rhinitis (AR), healthy people or nonallergic rhinitis (NAR) have shown contradicting results i......

The effects of secreted aspartyl proteinase inhibitor ritonavir on azoles-resistant strains of Candida albicans as well as regulatory role of SAP2 and ERG11

期刊: IMMUNITY INFLAMMATION AND DISEASE, 2021; 9 (3)

Background: Candida albicans, the main human fungal pathogen, can cause fungal infection and seriously affect people's health and life. This study aim......

Serum triglyceride levels and related factors as prognostic indicators in COVID-19 patients: A retrospective study

期刊: IMMUNITY INFLAMMATION AND DISEASE, 2021; 9 (3)

The role of triglycerides (TG) in coronavirus disease (COVID-19) is controversial. The objective of this study was to explore the relationship between......

Neutrophil extracellular traps induce thrombogenicity in severe carotid stenosis

期刊: IMMUNITY INFLAMMATION AND DISEASE, 2021; 9 (3)

Background: Severe carotid stenosis is a common cause of stroke. In addition, previous clinical studies revealed that patients symptomatic of carotid ......

lncRNA Mirt2 upregulates miR-1246 through methylation to suppress LPS-induced lung cell apoptosis

期刊: IMMUNITY INFLAMMATION AND DISEASE, 2021; 9 (3)

Introduction: Long noncoding RNA Mirt2 has been proven to be a suppressor of lipopolysaccharide (LPS) (a key player in sepsis)-induced inflammation re......

Ferulic acid suppresses interleukin-1 beta-induced degeneration of chondrocytes isolated from patients with osteoarthritis through the SIRT1/AMPK/PGC-1 alpha signaling pathway

期刊: IMMUNITY INFLAMMATION AND DISEASE, 2021; 9 (3)

Background: Interleukin-1 beta (IL-1 beta) is involved in osteoarthritis pathogenesis and mediates a series of toxic processes including the productio......

Activation of the cGAS-STING signaling pathway in adenomyosis patients

期刊: IMMUNITY INFLAMMATION AND DISEASE, 2021; 9 (3)

Objective: Adenomyosis is characterized by the presence of endometrium or endometrium-like glands and stroma within the myometrium. In this study, we ......

Circ_HECW2 regulates LPS-induced apoptosis of chondrocytes via miR-93 methylation

期刊: IMMUNITY INFLAMMATION AND DISEASE, 2021; 9 (3)

Introduction: Circ_HECW2 plays a key role in lipopolysaccharide (LPS)-induced signal transduction, which is critical in osteoarthritis (OA). Thus, we ......

The complex role of AIM2 in autoimmune diseases and cancers

期刊: IMMUNITY INFLAMMATION AND DISEASE, 2021; 9 (3)

Absent in melanoma 2 (AIM2) is a novel member of interferon (IFN)-inducible PYHIN proteins. In innate immune cells, AIM2 servers as a cytoplasmic doub......

LncRNA linc00152/NF-kappa B feedback loop promotes fibroblast-like synovial cells inflammation in rheumatoid arthritis via regulating miR-103a/TAK1 axis and YY1 expression

期刊: IMMUNITY INFLAMMATION AND DISEASE, 2021; 9 (3)

Introduction: Overexpressed inflammatory cytokines are the main factors causing rheumatoid arthritis (RA) tissue damage and pathological deterioration......

Comprehensive analysis of Syk gene methylation in colorectal cancer

期刊: IMMUNITY INFLAMMATION AND DISEASE, 2021; 9 (3)

Background: Metastasis of colorectal cancer (CRC) extremely affects the prognosis of CRC patients. Recently, the genetic methylation has been shown to......

Titanium dioxide nanotubes promote M2 polarization by inhibiting macrophage glycolysis and ultimately accelerate endothelialization

期刊: IMMUNITY INFLAMMATION AND DISEASE, 2021; 9 (3)

Titanium has been widely used in prosthetic valves, but they are associated with serious defects in titanium-based prosthetic valves, such as thrombos......

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