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Validation of Risk Assessment Models Predicting Venous Thromboembolism in Inpatients with Acute Exacerbation Of Chronic Obstructive Pulmonary Disease: A Multicenter Cohort Study in China

期刊: THROMBOSIS AND HAEMOSTASIS, 2022; 122 (7)

Background Inpatients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) are at increased risk for venous thromboembolism (VTE)......

JIF:3.887

Tetrahydrocurcumin Downregulates MAPKs/cPLA (2) Signaling and Attenuates Platelet Thromboxane A (2) Generation, Granule Secretion, and Thrombus Growth

期刊: THROMBOSIS AND HAEMOSTASIS, 2022; 122 (5)

Platelet granule secretion plays a key role in atherothrombosis. Curcumin, a natural polyphenol compound derived from turmeric, exerts multiple biolog......

JIF:3.887

Exploring Pleiotropic Effects of Lipid Modifiers and Targets on Measures of the Coagulation System with Genetics

期刊: THROMBOSIS AND HAEMOSTASIS, 2022; 122 (8)

Background Statins have long been suspected to have pleiotropic effects via thrombotic factors. Randomized controlled trials are too limited to be def......

JIF:3.887

Clopidogrel versus Ticagrelor in CYP2C19 Loss-of-Function Allele Noncarriers: A Real-World Study in China

期刊: THROMBOSIS AND HAEMOSTASIS, 2022; 122 (5)

Objective This article compares the clinical outcomes of clopidogrel and ticagrelor in patients with acute coronary syndrome (ACS) without cytochrome ......

JIF:3.887

Characteristics of the Thrombus Formation in Transgenic Mice with Platelet-Targeted Factor VIII Expression

期刊: THROMBOSIS AND HAEMOSTASIS, 2022; 122 (5)

Platelet-targeted FVIII gene therapy can efficiently recover bleeding phenotype for hemophilia A (HA), yet characteristics of thrombus formation with ......

JIF:3.887

Association of Combined Lifestyle and Polygenetic Risk with Incidence of Venous Thromboembolism: A Large Population-Based Cohort Study

期刊: THROMBOSIS AND HAEMOSTASIS, 2022; 122 (9)

As one of the fatal complications, venous thromboembolism (VTE) is associated with increased mortality. However, the combined effects of adopting mult......

JIF:3.887

Risk of Thromboembolic Events in Cancer Patients Treated with Immune Checkpoint Inhibitors: A Meta-analysis of Randomized Controlled Trials

期刊: THROMBOSIS AND HAEMOSTASIS, 2022; 122 (10)

Background The association between immune checkpoint inhibitors (ICIs) and thromboembolic events (TEEs) remains controversial. Objective The goal of t......

JIF:3.887

Atrial Fibrillation Detected by Single Time-Point Handheld Electrocardiogram Screening and the Risk of Ischemic Stroke

期刊: THROMBOSIS AND HAEMOSTASIS, 2022; 122 (2)

Objective We evaluated stroke risk in patients with single time-point screen-detected atrial fibrillation (AF) and the effect of oral anticoagulants (......

JIF:3.887

Impact of Asymptomatic Superior Mesenteric Vein Thrombosis on the Outcomes of Patients with Liver Cirrhosis

期刊: THROMBOSIS AND HAEMOSTASIS, 2022; 122 (12)

Background The impact of asymptomatic superior mesenteric vein (SMV) thrombosis on the outcomes of cirrhotic patients remains uncertain. Methods Nonma......

JIF:3.887

The COVID-19 Pandemic and the Need for an Integrated and Equitable Approach: An International Expert Consensus Paper

期刊: THROMBOSIS AND HAEMOSTASIS, 2021; 121 (8)

Background One year after the declaration of the coronavirus disease 2019 (COVID-19) pandemic by the World Health Organization (WHO) and despite the i......

Tumor Necrosis Factor-alpha Blockade Corrects Monocyte/Macrophage Imbalance in Primary Immune Thrombocytopenia

期刊: THROMBOSIS AND HAEMOSTASIS, ; ()

Primary immune thrombocytopenia (ITP) is an acquired autoimmune bleeding disorder. Monocytes and macrophages are the major cells involved in autoantib......

Comparison of Different Clinical Prognostic Scores in Patients with Pulmonary Embolism and Active Cancer

期刊: THROMBOSIS AND HAEMOSTASIS, ; ()

Objective This article aimed to validate and compare the prognostic performance of generic scores (Pulmonary Embolism Severity Index [PESI] and Hestia......

HSF1 Alleviates Microthrombosis and Multiple Organ Dysfunction in Mice with Sepsis by Upregulating the Transcription of Tissue-Type Plasminogen Activator

期刊: THROMBOSIS AND HAEMOSTASIS, ; ()

Sepsis is a life-threatening complication of infection closely associated with coagulation abnormalities. Heat shock factor 1 (HSF1) is an important t......

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