期刊： CHEMBIOCHEM, 2021; 22 (12)
There is a need of a non-homologous end joining (NHEJ) pathway reporter system that facilitates screening and discovery of NHEJ chemical inhibitors. I......
期刊： CHEMBIOCHEM, 2021; 22 (12)
Photodynamic therapy (PDT) has attracted great interest in cancer theranostics owing to its minimal invasiveness and low side effect. In PDT, photosen......
期刊： CHEMBIOCHEM, 2021; 22 (11)
Dopamine is an essential neurotransmitter and its detection is important for bioanalytical chemistry. Two very different DNA aptamers have been report......
期刊： CHEMBIOCHEM, 2021; 22 (11)
DNA N-6-methyladenine (6mA) has recently received notable attention due to an increased finding of its functional roles in higher eukaryotes. Here we ......
期刊： CHEMBIOCHEM, 2021; 22 (11)
The clustered regularly interspaced short palindromic repeats (CRISPR) technology has been widely applied for nucleic acid detection because of its hi......
期刊： CHEMBIOCHEM, 2021; 22 (14)
Functional nucleic acids (FNAs), including naturally occurring ribozymes and riboswitches as well as artificially created DNAzymes and aptamers, have ......
期刊： CHEMBIOCHEM, 2021; 22 (14)
DNA-encoded libraries (DEL) have come of age and become a major technology platform for ligand discovery in both academia and the pharmaceutical indus......
期刊： CHEMBIOCHEM, 2021; 22 (13)
Understanding the role of H2S in host defense mechanisms against RNA viruses may provide opportunities for the development of antivirals to combat vir......
期刊： CHEMBIOCHEM, 2021; 22 (16)
The conditional control of protein function in response to the physiological change of cells is of great interest for studying protein function in bio......
期刊： CHEMBIOCHEM, 2021; 22 (15)
Tyrosine plays important roles in many enzymes. To facilitate enzyme design, mechanistic studies and minimize structural perturbation in the active si......
期刊： CHEMBIOCHEM, 2021; 22 (15)
Hypoxia in aggressively proliferating tumor cells has been demonstrated to restrict the efficiency of photodynamic therapy owing to its oxygen (O-2)-d......
期刊： CHEMBIOCHEM, 2021; 22 (16)
The evolution of new SARS-CoV-2 variants around the globe has made the COVID-19 pandemic more worrisome, further pressuring the health care system and......
期刊： CHEMBIOCHEM, 2021; 22 (18)
Stapled peptides have been widely applied in many fields, including pharmaceutical chemistry, diagnostic reagents, and materials science. However, mos......
期刊： CHEMBIOCHEM, 2021; 22 (13)
Abnormal levels of glutathione, a cellular antioxidant, can lead to a variety of diseases. We have constructed a near-infrared ratiometric fluorescent......
The use of nicotinamide cytosine dinucleotide (NCD), a biocompatible nicotinamide adenosine dinucleotide (NAD) analogue, is of great scientific and bi......
