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Intervention of cGAS-STING signaling in sterile inflammatory diseases

期刊: JOURNAL OF MOLECULAR CELL BIOLOGY, 2022; 14 (2)

Sterile inflammation characterized by unresolved chronic inflammation is well established to promote the progression of multiple autoimmune diseases, ......

JIF:3.719

Structural insights reveal the specific recognition of meiRNA by the Mei2 protein

期刊: JOURNAL OF MOLECULAR CELL BIOLOGY, 2022; 14 (5)

In the fission yeast Schizosaccharomyces pombe, Mei2, an RNA-binding protein essential for entry into meiosis, regulates meiosis initiation. Mei2 bind......

JIF:3.719

The multifaceted functions of cGAS

期刊: JOURNAL OF MOLECULAR CELL BIOLOGY, 2022; 14 (5)

Pattern recognition receptors are critical for the sensing of pathogen-associated molecular patterns or danger-associated molecular patterns and subse......

JIF:3.719

Phosphorylation of CENP-R by Aurora B regulates kinetochore-microtubule attachment for accurate chromosome segregation

期刊: JOURNAL OF MOLECULAR CELL BIOLOGY, 2022; 14 (7)

Error-free mitosis depends on accurate chromosome attachment to spindle microtubules via a fine structure called the centromere that is epigenetically......

JIF:3.719

Deacetylation of MTHFD2 by SIRT4 senses stress signal to inhibit cancer cell growth by remodeling folate metabolism

期刊: JOURNAL OF MOLECULAR CELL BIOLOGY, 2022; 14 (4)

Folate metabolism plays an essential role in tumor development. Various cancers display therapeutic response to reagents targeting key enzymes of the ......

JIF:3.719

Intrinsic entropy model for feature selection of scRNA-seq data

期刊: JOURNAL OF MOLECULAR CELL BIOLOGY, 2022; 14 (2)

Recent advances of single-cell RNA sequencing (scRNA-seq) technologies have led to extensive study of cellular heterogeneity and cell-to-cell variatio......

JIF:3.719

Heart failure with preserved ejection fraction (HFpEF) in type 2 diabetes mellitus: from pathophysiology to therapeutics

期刊: JOURNAL OF MOLECULAR CELL BIOLOGY, 2022; 14 (5)

Type 2 diabetes mellitus (T2DM or T2D) is a devastating metabolic abnormality featured by insulin resistance, hyperglycemia, and hyperlipidemia. T2D p......

JIF:3.719

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