Lipids are a complex and diverse group of molecules with crucial roles in many physiological processes, as well as in the onset, progression, and main......
期刊： JHEP REPORTS, 2022; 4 (10)
Background & Aims: Pre-acute-on-chronic liver failure (ACLF) is a distinct intermediate stage between acute decompensation (AD) and ACLF. However,......
期刊： JHEP REPORTS, 2022; 4 (11)
Background & Aims: Non-absorbable inhibitors of the apical sodium-dependent bile acid transporter (ASBT; also called ileal bile acid transporter [......
Background & Aims: Increased serum bile acids (BAs) have been observed in patients with non-alcoholic steatohepatitis (NASH). Pegbelfermin (PGBF),......
Cure from chronic HBV infection is rare with current therapies. Basic research has helped to fundamentally improve our knowledge of the viral life cyc......
Non-alcoholic fatty liver disease (NAFLD) is reaching epidemic proportions, with a global prevalence of 25% in the adult population. Non-alcoholic ste......
Hepatopulmonary syndrome (HPS) is a pulmonary vascular complication of liver disease, which adversely affects prognosis. The disease is characterised ......
Transforming growth factor-beta (TGF-beta) is a potent effector in the liver, which is involved in a plethora of processes initiated upon liver injury......
Hepatocellular carcinoma (HCC) accounts for 90% of liver tumours and is one of the leading causes of mortality. Cirrhosis due to viral hepatitis, alco......
Background & Aims: Hepatic encephalopathy (HE) is a major complication after transjugular intrahepatic portosystemic shunt (TIPS) and is primarily......
Background & Aims: HDV affects 4.5-13% of chronic hepatitis B (CHB) patients globally, yet the prevalence of HDV infection in Canada is unknown. T......
期刊： JHEP REPORTS, 2022; 4 (10)
Background & Aims: Acetaminophen (APAP)-induced acute liver injury (ALI) is a global health issue characterised by an incomplete understanding of ......
期刊： JHEP REPORTS, 2022; 4 (11)
Background & Aims: People with primary sclerosing cholangitis (PSC) have a variable and often progressive disease course that is associated with b......
