期刊: EXPERIMENTAL CELL RESEARCH, 2022; 414 (1)
ICER is a transcriptional repressor that is mono-or poly-ubiquitinated. This either causes ICER to be translocated from the nucleus, or degraded via t......
期刊: EXPERIMENTAL CELL RESEARCH, 2022; 417 (1)
Parkinson's disease (PD) is a common neurodegenerative disease. Here, the purpose of the study was to explore the function of long non-coding RNA (lnc......
期刊: EXPERIMENTAL CELL RESEARCH, 2022; 418 (2)
Oxidative stress is considered a driving event in the damage to inner hair cell (IHC) synapses. Mitochondrial deacetylase sirtuin 3 (SIRT3) is an impo......
期刊: EXPERIMENTAL CELL RESEARCH, 2022; 419 (1)
Cholesterol homeostasis plays an important role in the maintenance of normal body functions. CYP27A1 is a key enzyme known to regulate cholesterol hom......
期刊: EXPERIMENTAL CELL RESEARCH, 2022; 419 (1)
Sorting nexins (SNXs) are involved in sorting the protein cargo within the endolysosomal system. Recently, several studies have shown the role of SNXs......
期刊: EXPERIMENTAL CELL RESEARCH, 2022; 419 (2)
Several studies have confirmed that exosomes containing microRNAs (miRNAs) from the aseptic inflammatory microenvironment play an important role in bo......
期刊: EXPERIMENTAL CELL RESEARCH, 2022; 420 (1)
Oxidative stress damage to the lens is a key factor in most cataracts. Forkhead box O 4 (FOXO4), a member of the forkhead box O family, plays a pivota......
期刊: EXPERIMENTAL CELL RESEARCH, 2022; 410 (1)
The ERK/MAPK signaling pathway is activated in various cancers including gastric cancer. Targeting the ERK/ MAPK/MEK pathway has been considered as a ......
期刊: EXPERIMENTAL CELL RESEARCH, 2022; 412 (2)
Schwann cells (SCs) play a critical role in peripheral nerve (PN) regeneration because of their ability to proliferate, migrate, and provide trophic s......
期刊: EXPERIMENTAL CELL RESEARCH, 2022; 413 (2)
Signal transducer and activator of transcription 3 (STAT3) plays key roles in cancer cell proliferation, invasion, and immunosuppression. In many huma......
期刊: EXPERIMENTAL CELL RESEARCH, 2022; 414 (1)
Background: Osteosarcoma (OS) is the most common primary bone malignancy. Circular RNAs (circRNAs) have been implicated in OS pathogenesis. In the cur......
期刊: EXPERIMENTAL CELL RESEARCH, 2022; 415 (2)
Serine hydroxymethyltransferase 2 (SHMT2) is a key enzyme that regulates serine/glycine transition; however, its specific function and molecular mecha......
期刊: EXPERIMENTAL CELL RESEARCH, 2022; 416 (2)
T-cell lymphoma (TCL) is a highly heterogeneous group of invasive non-Hodgkin lymphoma with adverse prognosis and limited treatment options. The relat......
期刊: EXPERIMENTAL CELL RESEARCH, 2022; 417 (2)
Induction of differentiation sensitizes chronic myeloid leukemia (CML) cells to the BCR-ABL inhibitor imatinib by mechanisms that remain unknown. We p......
期刊: EXPERIMENTAL CELL RESEARCH, 2022; 418 (1)
Pathological cardiac hypertrophy is an independent risk factor for the development of heart failure. Long noncoding RNAs (lncRNAs), an emerging class ......