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Roles of the tissue-type plasminogen activator in immune response

期刊: CELLULAR IMMUNOLOGY, 2022; 371 ()

The COVID-19 pandemic has once again brought to the forefront the existence of a tight link between the coagulation/fibrinolytic system and the immuno......

JIF:4.285

Restoring tolerance to 8-cells in Type 1 diabetes: Current and emerging strategies

期刊: CELLULAR IMMUNOLOGY, 2022; 380 ()

Type 1 diabetes (T1D) results from insulin insufficiency due to islet death and dysfunction following T cell -mediated autoimmune attack. The technica......

JIF:4.285

Adoptive transfer of activated immune cells against solid tumors: A preliminary study

期刊: CELLULAR IMMUNOLOGY, 2022; 382 ()

Background: This study presents preliminary results concerning the effectiveness of a novel immunotherapy in cancer. The proposed adoptive cellular th......

JIF:4.285

Relevance of Helminth-Microbiota interplay in the host immune response

期刊: CELLULAR IMMUNOLOGY, 2022; 374 ()

Helminths have been present throughout the evolution of humans, promoting the development and maturation of the host immune system. However, this inte......

JIF:4.285

Methyl butyrate attenuates concanavalin A-induced autoimmune hepatitis by inhibiting Th1-cell activation and homing to the liver

期刊: CELLULAR IMMUNOLOGY, 2022; 378 ()

Con A-induced hepatitis is the most commonly used animal model for simulating autoimmune hepatitis (AIH). In this study, we investigated whether methy......

JIF:4.285

Neutrophils, functions beyond host defense

期刊: CELLULAR IMMUNOLOGY, 2022; 379 ()

Neutrophils are the most abundant, ephemeral cell type in human blood. As the first line of defense in the host immune system, neutrophils mature in t......

JIF:4.285

Regulatory network of BLIMP1, IRF4, and XBP1 triad in plasmacytic differentiation and multiple myeloma pathogenesis

期刊: CELLULAR IMMUNOLOGY, 2022; 380 ()

Antibody secreting plasma cell plays an indispensable role in humoral immunity. As activated B cell undergoes germinal center reaction and develops in......

JIF:4.285

Nilabh Shastri-Towards understanding classical and non-classical MHC-I antigen processing and presentation

期刊: CELLULAR IMMUNOLOGY, 2022; 382 ()

Major histocompatibility complex (MHC-I) peptide antigen processing and presentation has experienced a revived interest in the context of immuno oncol......

JIF:4.285

BMDCs induce the generation of the CD103(+)CD8(+) tissue-resident memory T cell subtype, which amplifies local tumor control in the genital tract

期刊: CELLULAR IMMUNOLOGY, 2022; 374 ()

Tissue-resident memory T (Trm) cells can trigger a secondary immune response when they encounter the same antigen, playing an important role in antitu......

JIF:4.285

Age-associated B cells indicate disease activity in rheumatoid arthritis

期刊: CELLULAR IMMUNOLOGY, 2022; 377 ()

Age-associated B cells (ABCs) are characterized by CD11c and T-bet expression. ABCs are elevated in several autoimmune diseases and may be associated ......

JIF:4.285

Kinetics of antigen cross-presentation assessed experimentally and by a model of the complete endomembrane system

期刊: CELLULAR IMMUNOLOGY, 2022; 382 ()

Dendritic cells (DCs) have a specialized endomembrane system capable of presenting exogenous antigens in the context of MHC class I (MHC-I) molecules.......

JIF:4.285

Oral tolerance to prevent anti-drug antibody formation in protein replacement therapies

期刊: CELLULAR IMMUNOLOGY, 2022; 382 ()

Protein based therapeutics have successfully improved the quality of life for patients of monogenic disorders like hemophilia, Pompe and Fabry disease......

JIF:4.285

The lipid ties of alpha 1-antitrypsin: Structural and functional aspects

期刊: CELLULAR IMMUNOLOGY, 2022; 375 ()

alpha 1-antitrypsin (AAT) is an acute-phase protein that functions as an inhibitor of serine proteases, such as neutrophil elastase. A significant bod......

JIF:4.285

Dipeptidylcarboxypeptidase of Leishmania donovani: A potential vaccine molecule against experimental visceral leishmaniasis

期刊: CELLULAR IMMUNOLOGY, 2022; 375 ()

Visceral leishmaniasis is one of the deadliest parasitic diseases in the world. In the absence of an efficient and cost-effective drugs, development o......

JIF:4.285

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