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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 1
1998 2
2000 2
2002 1
2003 1
2004 3
2005 2
2007 1
2008 1
2009 1
2010 4
2011 3
2012 1
2013 5
2014 8
2015 5
2016 5
2017 3
2018 3
2019 3
2020 5
2021 3
2022 1
2023 2
2024 1

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63 results

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Page 1
When stem cells grow old: phenotypes and mechanisms of stem cell aging.
Schultz MB, Sinclair DA. Schultz MB, et al. Development. 2016 Jan 1;143(1):3-14. doi: 10.1242/dev.130633. Development. 2016. PMID: 26732838 Free PMC article. Review.
An attractive theory is that a loss in stem cell number and/or activity over time causes this decline. In accordance with this theory, aging phenotypes have been described for stem cells of multiple tissues, including those of the hematopoietic system, intestine, muscle, b …
An attractive theory is that a loss in stem cell number and/or activity over time causes this decline. In accordance with this theory, ag …
Conserved and novel functions of programmed cellular senescence during vertebrate development.
Davaapil H, Brockes JP, Yun MH. Davaapil H, et al. Development. 2017 Jan 1;144(1):106-114. doi: 10.1242/dev.138222. Epub 2016 Nov 25. Development. 2017. PMID: 27888193 Free PMC article.
Our findings uncover conserved and new roles of senescence in vertebrate organogenesis and support the view that cellular senescence may have arisen in evolution as a developmental mechanism....
Our findings uncover conserved and new roles of senescence in vertebrate organogenesis and support the view that cellular senescence may hav …
Cell competition: the winners and losers of fitness selection.
Bowling S, Lawlor K, Rodríguez TA. Bowling S, et al. Development. 2019 Jul 5;146(13):dev167486. doi: 10.1242/dev.167486. Development. 2019. PMID: 31278123 Free article. Review.
The process has a myriad of positive roles in the organism: it selects against mutant cells in developing tissues, prevents the propagation of oncogenic cells and eliminates damaged cells during ageing. However, 'super-fit' cancer cells can exploit cell competition mech …
The process has a myriad of positive roles in the organism: it selects against mutant cells in developing tissues, prevents the propagation …
Involvement of Wnt, Eda and Shh at defined stages of sweat gland development.
Cui CY, Yin M, Sima J, Childress V, Michel M, Piao Y, Schlessinger D. Cui CY, et al. Development. 2014 Oct;141(19):3752-60. doi: 10.1242/dev.109231. Development. 2014. PMID: 25249463 Free PMC article.
To maintain body temperature, sweat glands develop from embryonic ectoderm by a poorly defined mechanism. We demonstrate a temporal cascade of regulation during mouse sweat gland formation. ...
To maintain body temperature, sweat glands develop from embryonic ectoderm by a poorly defined mechanism. We demonstrate a temporal c …
Tet family proteins and 5-hydroxymethylcytosine in development and disease.
Tan L, Shi YG. Tan L, et al. Development. 2012 Jun;139(11):1895-902. doi: 10.1242/dev.070771. Development. 2012. PMID: 22569552 Free PMC article. Review.
Over the past few decades, DNA methylation at the 5-position of cytosine (5-methylcytosine, 5mC) has emerged as an important epigenetic modification that plays essential roles in development, aging and disease. However, the mechanisms controlling 5mC dynamics remain …
Over the past few decades, DNA methylation at the 5-position of cytosine (5-methylcytosine, 5mC) has emerged as an important epigenetic modi …
Intrinsic and extrinsic mechanisms regulating satellite cell function.
Dumont NA, Wang YX, Rudnicki MA. Dumont NA, et al. Development. 2015 May 1;142(9):1572-81. doi: 10.1242/dev.114223. Development. 2015. PMID: 25922523 Free PMC article. Review.
Thus, a complex balance between extrinsic cues and intrinsic regulatory mechanisms is needed to tightly control satellite cell cycle progression and cell fate determination. Defects in satellite cell regulation or in their niche, as observed in degenerative conditions such …
Thus, a complex balance between extrinsic cues and intrinsic regulatory mechanisms is needed to tightly control satellite cell cycle …
Transient and lineage-restricted requirement of Ebf3 for sternum ossification.
Kuriki M, Sato F, Arai HN, Sogabe M, Kaneko M, Kiyonari H, Kawakami K, Yoshimoto Y, Shukunami C, Sehara-Fujisawa A. Kuriki M, et al. Development. 2020 May 12;147(9):dev186239. doi: 10.1242/dev.186239. Development. 2020. PMID: 32398354 Free PMC article.
Osteoblasts arise from bone-surrounding connective tissue containing tenocytes and fibroblasts. Lineages of these cell populations and mechanisms of their differentiation are not well understood. Screening enhancer-trap lines of zebrafish allowed us to identify Ebf3 as a t …
Osteoblasts arise from bone-surrounding connective tissue containing tenocytes and fibroblasts. Lineages of these cell populations and me …
MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus.
Kaiser K, Jang A, Kompanikova P, Lun MP, Prochazka J, Machon O, Dani N, Prochazkova M, Laurent B, Gyllborg D, van Amerongen R, Fame RM, Gupta S, Wu F, Barker RA, Bukova I, Sedlacek R, Kozmik Z, Arenas E, Lehtinen MK, Bryja V. Kaiser K, et al. Development. 2021 May 15;148(10):dev192054. doi: 10.1242/dev.192054. Epub 2021 May 25. Development. 2021. PMID: 34032267 Free PMC article.
ChP tissues form in each brain ventricle, each one adopting a distinct shape, but remarkably little is known about the mechanisms underlying ChP development. Here, we show that epithelial WNT5A is crucial for determining fourth ventricle (4V) ChP morphogenesis and size in …
ChP tissues form in each brain ventricle, each one adopting a distinct shape, but remarkably little is known about the mechanisms und …
Mechanosensory neuron regeneration in adult Drosophila.
Fernández-Hernández I, Marsh EB, Bonaguidi MA. Fernández-Hernández I, et al. Development. 2021 Mar 10;148(5):dev187534. doi: 10.1242/dev.187534. Development. 2021. PMID: 33597190 Free PMC article.
Auditory and vestibular mechanosensory hair cells do not regenerate following injury or aging in the adult mammalian inner ear, inducing irreversible hearing loss and balance disorders for millions of people. ...Our findings introduce a new platform to expedite research on …
Auditory and vestibular mechanosensory hair cells do not regenerate following injury or aging in the adult mammalian inner ear, induc …
63 results