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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1880 1
1887 1
1894 1
1912 1
1913 1
1920 1
1923 2
1944 1
1946 3
1947 5
1948 4
1949 3
1950 4
1951 7
1952 4
1953 7
1954 5
1955 3
1956 4
1957 5
1958 5
1959 5
1960 6
1961 6
1962 5
1963 20
1964 26
1965 26
1966 21
1967 34
1968 77
1969 81
1970 82
1971 107
1972 102
1973 70
1974 108
1975 111
1976 102
1977 78
1978 85
1979 115
1980 108
1981 94
1982 106
1983 118
1984 111
1985 126
1986 131
1987 206
1988 332
1989 378
1990 558
1991 564
1992 592
1993 644
1994 817
1995 803
1996 873
1997 1070
1998 1137
1999 1325
2000 1738
2001 1842
2002 2150
2003 2484
2004 3108
2005 3796
2006 4321
2007 4938
2008 5522
2009 6187
2010 7330
2011 8269
2012 9705
2013 12241
2014 19798
2015 24950
2016 29041
2017 32415
2018 36330
2019 40894
2020 48857
2021 57255
2022 62404
2023 60991
2024 29942
2025 5

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464,034 results

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Page 1
Engineering precision nanoparticles for drug delivery.
Mitchell MJ, Billingsley MM, Haley RM, Wechsler ME, Peppas NA, Langer R. Mitchell MJ, et al. Nat Rev Drug Discov. 2021 Feb;20(2):101-124. doi: 10.1038/s41573-020-0090-8. Epub 2020 Dec 4. Nat Rev Drug Discov. 2021. PMID: 33277608 Free PMC article. Review.
As lipid-based, polymeric and inorganic nanoparticles are engineered in increasingly specified ways, they can begin to be optimized for drug delivery in a more personalized manner, entering the era of precision medicine. ...
As lipid-based, polymeric and inorganic nanoparticles are engineered in increasingly specified ways, they can begin to be optimized f …
Applications of synthetic biology in medical and pharmaceutical fields.
Yan X, Liu X, Zhao C, Chen GQ. Yan X, et al. Signal Transduct Target Ther. 2023 May 11;8(1):199. doi: 10.1038/s41392-023-01440-5. Signal Transduct Target Ther. 2023. PMID: 37169742 Free PMC article. Review.
During the past decades, progresses have been made to build delicate biocircuits, standardized biological building blocks and to develop various genomic/metabolic engineering tools and approaches. Medical and pharmaceutical demands have also pushed the develo …
During the past decades, progresses have been made to build delicate biocircuits, standardized biological building blocks and to develop var …
Recent advances in hydrogels for cartilage tissue engineering.
Vega SL, Kwon MY, Burdick JA. Vega SL, et al. Eur Cell Mater. 2017 Jan 30;33:59-75. doi: 10.22203/eCM.v033a05. Eur Cell Mater. 2017. PMID: 28138955 Free PMC article. Review.
Limitations of current treatments for cartilage defects have prompted the field of cartilage tissue engineering, which seeks to integrate engineering and biological principles to promote the growth of new cartilage to replace damaged tissue. ...Some of these advance …
Limitations of current treatments for cartilage defects have prompted the field of cartilage tissue engineering, which seeks to integ …
Understanding pharmaceutical quality by design.
Yu LX, Amidon G, Khan MA, Hoag SW, Polli J, Raju GK, Woodcock J. Yu LX, et al. AAPS J. 2014 Jul;16(4):771-83. doi: 10.1208/s12248-014-9598-3. Epub 2014 May 23. AAPS J. 2014. PMID: 24854893 Free PMC article. Review.
This review further clarifies the concept of pharmaceutical quality by design (QbD) and describes its objectives. QbD elements include the following: (1) a quality target product profile (QTPP) that identifies the critical quality attributes (CQAs) of the drug product; (2) …
This review further clarifies the concept of pharmaceutical quality by design (QbD) and describes its objectives. QbD elements includ …
Engineering Three-Dimensional Vascularized Cardiac Tissues.
Williams MAC, Mair DB, Lee W, Lee E, Kim DH. Williams MAC, et al. Tissue Eng Part B Rev. 2022 Apr;28(2):336-350. doi: 10.1089/ten.TEB.2020.0343. Epub 2021 Mar 16. Tissue Eng Part B Rev. 2022. PMID: 33559514 Free PMC article. Review.
Impact statement The field of cardiac tissue engineering is rapidly evolving and is now closer than ever to having engineered tissue models capable of predicting preclinical responses to therapeutics, modeling diseases, and being used as a means of rescuing cardiac …
Impact statement The field of cardiac tissue engineering is rapidly evolving and is now closer than ever to having engineered …
Engineering consortia by polymeric microbial swarmbots.
Wang L, Zhang X, Tang C, Li P, Zhu R, Sun J, Zhang Y, Cui H, Ma J, Song X, Zhang W, Gao X, Luo X, You L, Chen Y, Dai Z. Wang L, et al. Nat Commun. 2022 Jul 5;13(1):3879. doi: 10.1038/s41467-022-31467-1. Nat Commun. 2022. PMID: 35790722 Free PMC article.
In soil, multiple species can coexist with a spatial organization. Inspired by nature, here we show that an engineered spatial segregation method can assemble stable consortia with both flexibility and precision. ...Our work integrates the synthetic biology and material sc …
In soil, multiple species can coexist with a spatial organization. Inspired by nature, here we show that an engineered spatial segreg …
Chemical Engineering in the "BIO" World.
Chiarappa G, Grassi M, Abrami M, Abbiati RA, Barba AA, Boisen A, Brucato V, Ghersi G, Caccavo D, Cascone S, Caserta S, Elvassore N, Giomo M, Guido S, Lamberti G, Larobina D, Manca D, Marizza P, Tomaiuolo G, Grassi G. Chiarappa G, et al. Curr Drug Deliv. 2017;14(2):158-178. doi: 10.2174/1567201813666160602230550. Curr Drug Deliv. 2017. PMID: 27264726 Review.
Whitaker, in 1914, affirmed that the difference between Chemistry and Chemical Engineering lies in the capability of chemical engineers to transfer laboratory findings to the industrial level. ...The beginning of the sixties of the 20th century saw the development o …
Whitaker, in 1914, affirmed that the difference between Chemistry and Chemical Engineering lies in the capability of chemical engi …
Engineering hydrogels for personalized disease modeling and regenerative medicine.
Tayler IM, Stowers RS. Tayler IM, et al. Acta Biomater. 2021 Sep 15;132:4-22. doi: 10.1016/j.actbio.2021.04.020. Epub 2021 Apr 18. Acta Biomater. 2021. PMID: 33882354 Review.
Here, we review recent progress in the use of hydrogels to create artificial cellular microenvironments for personalized tissue engineering and regenerative medicine applications, as well as to develop personalized disease models. We highlight engineering strategies …
Here, we review recent progress in the use of hydrogels to create artificial cellular microenvironments for personalized tissue engineeri …
Engineered Living Hydrogels.
Liu X, Inda ME, Lai Y, Lu TK, Zhao X. Liu X, et al. Adv Mater. 2022 Jul;34(26):e2201326. doi: 10.1002/adma.202201326. Epub 2022 Apr 24. Adv Mater. 2022. PMID: 35243704 Free PMC article. Review.
Living biological systems, ranging from single cells to whole organisms, can sense, process information, and actuate in response to changing environmental conditions. Inspired by living biological systems, engineered living cells and nonliving matrices are brought together …
Living biological systems, ranging from single cells to whole organisms, can sense, process information, and actuate in response to changing …
Photobiomodulation in 3D tissue engineering.
Bikmulina P, Kosheleva N, Shpichka A, Yusupov V, Gogvadze V, Rochev Y, Timashev P. Bikmulina P, et al. J Biomed Opt. 2022 Sep;27(9):090901. doi: 10.1117/1.JBO.27.9.090901. J Biomed Opt. 2022. PMID: 36104833 Free PMC article.
AIM: We aim to discuss the PBM and 3D tissue engineered constructs to define the fields of interest for PBM applications in tissue engineering. ...Because of the poor viability of cells in scaffolds and the convenience of PBM devices, 3D tissue engineering is …
AIM: We aim to discuss the PBM and 3D tissue engineered constructs to define the fields of interest for PBM applications in tissue …
464,034 results
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