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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1989 6
1990 3
1991 8
1992 5
1993 13
1994 3
1995 13
1996 11
1997 13
1998 13
1999 2
2000 14
2001 13
2002 4
2003 26
2004 90
2005 64
2006 78
2007 79
2008 85
2009 98
2010 103
2011 85
2012 87
2013 117
2014 138
2015 140
2016 157
2017 145
2018 195
2019 218
2020 273
2021 308
2022 285
2023 320
2024 107

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3,235 results

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Page 1
Integrative single-cell RNA-seq and ATAC-seq analysis of myogenic differentiation in pig.
Cai S, Hu B, Wang X, Liu T, Lin Z, Tong X, Xu R, Chen M, Duo T, Zhu Q, Liang Z, Li E, Chen Y, Li J, Liu X, Mo D. Cai S, et al. BMC Biol. 2023 Feb 1;21(1):19. doi: 10.1186/s12915-023-01519-z. BMC Biol. 2023. PMID: 36726129 Free PMC article.
Skeletal muscle initiates in the somites, with muscle precursor cells generated in the dermomyotome and dermomyotome-derived myotome before muscle differentiation ensues, a developmentally regulated process that is well characterized in model organisms. ...CONCLUSIONS: Col …
Skeletal muscle initiates in the somites, with muscle precursor cells generated in the dermomyotome and dermomyotome-derived myotome …
Sex-limited chromosomes and non-reproductive traits.
Cīrulis A, Hansson B, Abbott JK. Cīrulis A, et al. BMC Biol. 2022 Jul 6;20(1):156. doi: 10.1186/s12915-022-01357-5. BMC Biol. 2022. PMID: 35794589 Free PMC article. Review.
Here, we provide an overview of the effects of sex-limited chromosomes on non-reproductive traits in XY, ZW or UV sex determination systems, and discuss evolutionary processes maintaining variation at sex-limited chromosomes and molecular mechanisms affecting non-reproduct …
Here, we provide an overview of the effects of sex-limited chromosomes on non-reproductive traits in XY, ZW or UV sex determination systems, …
Ultrastructural and molecular analysis of the origin and differentiation of cells mediating brittle star skeletal regeneration.
Piovani L, Czarkwiani A, Ferrario C, Sugni M, Oliveri P. Piovani L, et al. BMC Biol. 2021 Jan 18;19(1):9. doi: 10.1186/s12915-020-00937-7. BMC Biol. 2021. PMID: 33461552 Free PMC article.
Both mechanisms have been described in different phyla; however, the cellular and molecular mechanisms employed by different animals to restore lost tissues as well as the source of cells involved in regeneration remain largely unknown. ...Here, we use the br …
Both mechanisms have been described in different phyla; however, the cellular and molecular mechanisms employed by different a …
Shaping the dynamic mitochondrial network.
Lackner LL. Lackner LL. BMC Biol. 2014 May 27;12:35. doi: 10.1186/1741-7007-12-35. BMC Biol. 2014. PMID: 24884775 Free PMC article. Review.
Maintaining the shape of this complex network is critical for both mitochondrial and cellular function and involves the activities of mitochondrial division, fusion, motility, and tethering. Recent studies have advanced our understanding of the molecular mechanisms …
Maintaining the shape of this complex network is critical for both mitochondrial and cellular function and involves the activities of …
An IGF1-expressing endometrial stromal cell population is associated with human decidualization.
Shi JW, Lai ZZ, Yang HL, Zhou WJ, Zhao XY, Xie F, Liu SP, Chen WD, Zhang T, Ye JF, Zhou XY, Li MQ. Shi JW, et al. BMC Biol. 2022 Dec 8;20(1):276. doi: 10.1186/s12915-022-01483-0. BMC Biol. 2022. PMID: 36482461 Free PMC article.
Despite the increasing number of genes reportedly associated with endometrial receptivity and decidualization, the cellular and molecular mechanisms triggering and underlying decidualization remain largely unknown. Here, we analyze single-cell transcriptional profil …
Despite the increasing number of genes reportedly associated with endometrial receptivity and decidualization, the cellular and mo …
Plasma membrane integrity: implications for health and disease.
Ammendolia DA, Bement WM, Brumell JH. Ammendolia DA, et al. BMC Biol. 2021 Apr 13;19(1):71. doi: 10.1186/s12915-021-00972-y. BMC Biol. 2021. PMID: 33849525 Free PMC article. Review.
Plasma membrane integrity is essential for cellular homeostasis. In vivo, cells experience plasma membrane damage from a multitude of stressors in the extra- and intra-cellular environment. To avoid lethal consequences, cells are equipped with repair p …
Plasma membrane integrity is essential for cellular homeostasis. In vivo, cells experience plasma membrane damage from a multi …
Hsp70 at the membrane: driving protein translocation.
Craig EA. Craig EA. BMC Biol. 2018 Jan 17;16(1):11. doi: 10.1186/s12915-017-0474-3. BMC Biol. 2018. PMID: 29343244 Free PMC article. Review.
The translocation process is particularly challenging when the channel in the membrane through which proteins must pass is narrow-such as those in the membranes of the endoplasmic reticulum and mitochondria. Hsp70 molecular chaperones play roles on both sides of these memb …
The translocation process is particularly challenging when the channel in the membrane through which proteins must pass is narrow-such as th …
Single-cell and spatial transcriptomics reveal changes in cell heterogeneity during progression of human tendinopathy.
Fu W, Yang R, Li J. Fu W, et al. BMC Biol. 2023 Jun 6;21(1):132. doi: 10.1186/s12915-023-01613-2. BMC Biol. 2023. PMID: 37280595 Free PMC article.
Tendinopathy is one of the most common diseases associated with musculoskeletal tissue degeneration, representing a major global healthcare burden that affects both athletes and the general population, with the clinical presentation of long-term recurring chronic pain and decreas …
Tendinopathy is one of the most common diseases associated with musculoskeletal tissue degeneration, representing a major global healthcare …
Disruption of left-right axis specification in Ciona induces molecular, cellular, and functional defects in asymmetric brain structures.
Kourakis MJ, Bostwick M, Zabriskie A, Smith WC. Kourakis MJ, et al. BMC Biol. 2021 Jul 13;19(1):141. doi: 10.1186/s12915-021-01075-4. BMC Biol. 2021. PMID: 34256748 Free PMC article.
Here, we explore the consequences of disrupting left-right axis specification on Ciona larval CNS cellular anatomy, gene expression, synaptic connectivity, and behavior. ...
Here, we explore the consequences of disrupting left-right axis specification on Ciona larval CNS cellular anatomy, gene expression, …
Stem cell-derived porcine macrophages as a new platform for studying host-pathogen interactions.
Meek S, Watson T, Eory L, McFarlane G, Wynne FJ, McCleary S, Dunn LEM, Charlton EM, Craig C, Shih B, Regan T, Taylor R, Sutherland L, Gossner A, Chintoan-Uta C, Fletcher S, Beard PM, Hassan MA, Grey F, Hope JC, Stevens MP, Nowak-Imialek M, Niemann H, Ross PJ, Tait-Burkard C, Brown SM, Lefevre L, Thomson G, McColl BW, Lawrence AB, Archibald AL, Steinbach F, Crooke HR, Gao X, Liu P, Burdon T. Meek S, et al. BMC Biol. 2022 Jan 14;20(1):14. doi: 10.1186/s12915-021-01217-8. BMC Biol. 2022. PMID: 35027054 Free PMC article.
RESULTS: We explored how porcine pluripotent stem cells (PSCs) can provide a limitless in vitro supply of genetically and experimentally tractable macrophages. ...Moreover, porcine PSCdMs were readily amenable to genetic modification by CRISPR/Cas9 gene editing applied eit …
RESULTS: We explored how porcine pluripotent stem cells (PSCs) can provide a limitless in vitro supply of genetically and experimenta …
3,235 results