STROKE:磁敏感血管征--预测脑卒中亚型和血运重建术后疗效

2017-06-14 shaosai MedSci原创

磁敏感血管征(SVS)是指在磁敏感图像上的低信号,该征象是由于局部血栓所产生的磁敏感效应。这在磁共振磁敏感加权图像上是很容易辨别的。然而,SVS特征与脑卒中亚型分类以及介入治疗后血运再通疗效之间的关系尚不明确。近日,有研究人员在心血管权威杂志STROKE中发表了他们的研究成果。本研究共纳入了89例大脑前循环急性脑卒中的患者,并在行血管内治疗前进行MRI SWI扫描。采用盲法,阅片者对患者的脑卒中亚

磁敏感血管征(SVS)是指在磁敏感图像上的低信号,该征象是由于局部血栓所产生的磁敏感效应。这在磁共振磁敏感加权图像上是很容易辨别的。然而,SVS特征与脑卒中亚型分类以及介入治疗后血运再通疗效之间的关系尚不明确。近日,有研究人员在心血管权威杂志STROKE中发表了他们的研究成果。

本研究共纳入了89例大脑前循环急性脑卒中的患者,并在行血管内治疗前进行MRI SWI扫描。采用盲法,阅片者对患者的脑卒中亚型分类及术后再通状态未知,独立测量SVS的直径、长度和体积。然后对以上组间及组内数据进行分析。

研究结果得出,在78%的患者中出现了SVS。与非心源性栓塞患者相比,SVS更常见于心源性栓塞的患者(P = 0.01);同时,心源性栓塞组SVS直径(P <0.01)和长度(P = 0.01)也相对大于非心源性患者组。行血运再通组SVS直径(脑梗死溶栓≥2b)要高于未行血运再通组(P = 0.04)。多变量分析显示,SVS直径可作为心源性栓塞的独立预测因子(调整后OR值为1.97; 95%CI,1.34-2.90; P <0.01)。而SVS体积与血运再通后疗效之间无显着相关统计学意义(调整后OR值为1.003; 95%CI,0.999-1.006; P = 0.12)。心源性栓塞的SVS直径cutoff值为5.5 mm(敏感度为45.6%,特异度为93.8%)。

研究表明,敏感度加权磁共振成像上的SVS直径增加能够作为预测心源性栓塞的标志物。SVS体积与血运再通疗效间并无显着地相关。

原始出处:

Dong-Wan Kang, Han-Gil Jeong, Do Yeon Kim, et al. Prediction of Stroke Subtype and Recanalization Using Susceptibility Vessel Sign on Susceptibility-Weighted Magnetic Resonance Imaging. Stroke. 2017. DOI: 10.1161/STROKEAHA.116.016217

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    2017-06-30 shaosai

    好好学习,涨知识

    0

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    2017-06-15 shaosai

    谢谢分享

    0

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