Am J Med:局部或转移性癌患者下腔静脉滤器使用比较

2016-08-24 Moon 译 MedSci原创

转移性癌和静脉血栓栓塞症患者常常会有抗凝治疗禁忌症,进而促使了可回收下腔静脉滤器的使用。本研究的目的是比较局部与转移性癌患者的下腔静脉滤器使用模式、抗凝管理和下腔静脉滤器相关并发症的发展。我们进行了一项回顾性队列研究,纳入了只有局部或转移性癌患者,记录了下腔静脉滤器的适应症,植入滤器后的抗凝管理、回收率和相关并发症。总体而言,154例癌患者接受下腔静脉滤器置入术。局部或转移性癌患者的基线人口统计资

转移性癌和静脉血栓栓塞症患者常常会有抗凝治疗禁忌症,进而促使了可回收下腔静脉滤器的使用。本研究的目的是比较局部与转移性癌患者的下腔静脉滤器使用模式、抗凝管理和下腔静脉滤器相关并发症的发展。

我们进行了一项回顾性队列研究,纳入了只有局部或转移性癌患者,记录了下腔静脉滤器的适应症,植入滤器后的抗凝管理、回收率和相关并发症。

总体而言,154例癌患者接受下腔静脉滤器置入术。局部或转移性癌患者的基线人口统计资料和滤器位置相似。转移性癌患者有更多的滤器相关并发症(25% vs. 11%, p=0.03);滤器回收率更低(31% vs. 58%, p=0.01);重新开始抗凝治疗的时间更长(5.5天vs. 2天, p=0.05)。在多变量分析中,转移性疾病与下腔静脉滤器回收率的下降有关(OR 0.3, p=0.003)。使用抗凝治疗与更低的滤器相关并发症有关(OR 0.3, p=0.005)。

转移性癌患者留置下腔静脉滤器有较高的滤器相关并发症、较低的滤器回收率和较长的启动抗凝治疗中位时间。 在可能的情况下,早期抗凝治疗可减少下腔静脉滤器相关并发症。

原始出处:

Mahmood SS.et al.Anticoagulation is Associated with Decreased Inferior Vena Cava Filter-Related Complications in Metastatic Carcinoma Patients.Am J Med. 2016 Jul 28. pii: S0002-9343(16)30736-7. doi: 10.1016/j.amjmed.2016.06.048. [Epub ahead of print]


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    2017-01-06 fusion
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    2016-08-30 李东泽

    很好,不错,以后会多学习

    0

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    2016-08-26 chg122
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    2016-08-26 ylzr123

    深度好文,赞一个!!!

    0

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