Diabetic Med:1991年至2013年英国Ⅱ型糖尿病患病率,血糖控制和相对生存率如何?

2017-06-23 MedSci MedSci原创

近日,国际杂志《Diabetic medicine》上在线发表1991年至2013年英国2型糖尿病患病率,血糖控制和相对生存率,并确定在此期间糖尿病患者的相应葡萄糖控制和存活率是否发生变化。

近日,国际杂志《Diabetic medicine》上在线发表1991年至2013年英国2糖尿病患病率,血糖控制和相对生存率,并确定在此期间糖尿病患者的相应葡萄糖控制和存活率是否发生变化。

研究人员使用回顾性队列研究,从临床实践研究数据库(CPRD)中获得1991年至2013年期间确诊为2糖尿病的人群数据,并计算年度流行率。估计年平均HbA 1c。利用Cox比例风险模型计算年度降糖治疗2型糖尿病例数全因死亡率的风险。

2型糖尿病的粗略患病率从1991年的1.32%(95CI1.30-1.34%)增加到2013年的4.54%(4.52-4.56%)。2型糖尿病患者的平均HbA 1c 1991年为71 mmol / mol8.6%),2003年为59 mmol / mol7.5%),2013年为58 mmol / mol7.5%)。与1991年比较,在2013年,经治疗的2型糖尿病患者的全因死亡率的风险比为0.330.27-0.41)。

英国2型糖尿病患病率在1991年至2013年期间在出现了三倍增长。2型糖尿病患者的生存率提高有可能在一定程度上来解释观察到的患病增加。

原始出处:

S. E. Holden, S. Jenkins-Jones, C. Ll. Morgan,et al. Prevalence, glucose control and relative survival of people with Type 2 diabetes in the UK from 1991 to 2013

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  8. 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  9. 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    2017-06-24 189****7206

    学习了谢谢分享

    0

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    2017-06-24 惠映实验室

    学习了,谢谢分享

    0

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近日,国际杂志《Diabetic Medicine》在线发表了一项关于评估使用自我收集的毛细血管样品进行胰岛自身抗体检测以鉴定1型糖尿病患者亲属风险的可行性的研究。

Diabetic Med:与正常人群相比糖尿病母亲的后代的死亡率和发病率并无差异

近日,国际杂志 《Diabetic medicine》上在线发表一项关于与正常人群相比,糖尿病母亲的后代的死亡率和发病率的队列研究。研究人员将691名糖尿病母亲后代的死亡率,住院天数,诊断类别和糖尿病发病率与168 831名无糖尿病母亲后代进行比较。从北日特兰妊娠数据库抽取1976年至2003年间出生的(521例1型; 34例2型; 136例妊娠糖尿病)糖尿病母亲的后代。结果数据从国家病人登记处检

Diabetic Med:医院低血糖和高血糖的季节性变化

近日,国际杂志《Diabetic medicine》上在线发表一项关于评估医院低血糖和高血糖症的发生率是否显示季节变化的研究。 研究人员使用医疗相关保健数据库数据运用时间序列分析加拿大安大略省2003年至2012年期间每月住院病例(急诊室或住院患者)的低血糖和高血糖情况。

Diabetic Med:澳大利亚城市原住民死亡率和心血管疾病风险与糖尿病和蛋白尿的关联

近日,国际杂志《Diabetic medicine》上在线发表一项关于澳大利亚城市原住民死亡率和心血管疾病风险与糖尿病和蛋白尿的关联的跟踪研究。

JCEM:胰腺脂肪沉积对胰岛β细胞减少的影响

糖尿病是由于胰岛素绝对或相对不足引起的一种以慢性高血糖为特征的代谢性疾病,胰岛β细胞功能损伤和/或数量减少是各型糖尿病的共同特征和发病基础。2型糖尿病的一大特征在于胰腺中胰岛素表达水平降低。科学家们通常认为这种下降的原因在于这种器官中胰岛β细胞死亡。但是在2型糖尿病病人的胰腺中,人们很少发现死亡的β细胞。而且胰腺功能障碍与死亡的β细胞数量不成比例。目前的研究仍无法解释2型糖尿病(T2DM)患者胰岛