BMC Oral Health:侵袭性牙周炎的治疗:辅助应用抗生素or PDT,哪个更有效?

2015-07-27 sunshine 译 MedSci原创

 本研究的目的是为了评估非手术治疗方法联合全身抗生素(AB)应用或光动力疗法(PDT)对侵袭性牙周炎(AgP)患者龈沟液中基质金属蛋白酶8(MMP-8)和基质金属蛋白酶9(MMP-9)浓度的影响。研究纳入了36名侵袭性牙周炎患者,将其随机分配为两组。一组患者在接受全身抗生素(如阿莫西林+甲硝唑)用药后,进行洁刮治和根面平整(SRP);另一组患者则接受SRP+PDT治疗。治疗前及治疗后第3

 
本研究的目的是为了评估非手术治疗方法联合全身抗生素(AB)应用或光动力疗法(PDT)对侵袭性牙周炎(AgP)患者龈沟液中基质金属蛋白酶8(MMP-8)和基质金属蛋白酶9(MMP-9)浓度的影响。

研究纳入了36名侵袭性牙周炎患者,将其随机分配为两组。一组患者在接受全身抗生素(如阿莫西林+甲硝唑)用药后,进行洁刮治和根面平整(SRP);另一组患者则接受SRP+PDT治疗。治疗前及治疗后第3个月和治疗后第6个月时分别评估分析患者龈沟液内MMP-8和MMP-9的浓度。使用非参数曼-惠特尼U检验进行两两比较。采用弗里德曼方差分析法与Kendall一致性检验分析MMP-8及MMP-9从基线时期至治疗后3个月和治疗后6个月时浓度的变化。
 
结果发现,采用抗生素全身用药后再行SRP组,在治疗后第3个月及第6个月时,患者龈沟液内MMP-8的水平较基线时期明显降低,差异具有统计学意义(p = 0.01),而SRP+PDT组,患者龈沟液内MMP-8的水平变化则无统计学意义。两组患者龈沟液内MMP-9的水平在治疗后第3个月及第6个月时均有所下降,但是这种变化并无统计学意义。

总而言之,本研究发现,侵袭性牙周炎患者非手术治疗方法联合阿莫西林和甲硝唑辅助全身用药较联合PDT应用能更有效地降低龈沟液内MMP-8的水平。

原始出处:

Anna Skurska; Ewa Dolinska; MaナHorzata Pietruska; Jan K. Pietruski; Violetta Dymicka; Halina Kemona; Nicole B. Arweiler; Robert Milewski; Anton Sculean.Aggressive Periodontitis: Antibiotics or PDT as an Adjunct?BMC Oral Health. 2015;15(63) 

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    2016-09-13 1e10c84am36(暂无匿称)

    好文章,还会关注

    0

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    2015-12-05 shizhenshan
  3. 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    2016-06-02 小几洁
  4. 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createdName=shizhenshan, createdTime=Sat Dec 05 01:26:00 CST 2015, time=2015-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020175, encodeId=7e1220201e5c1, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Thu Jun 02 21:26:00 CST 2016, time=2016-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974617, encodeId=8c6619e461768, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Wed Aug 12 16:26:00 CST 2015, time=2015-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1661516, encodeId=bb67166151625, content=<a href='/topic/show?id=73a3139e4e9' target=_blank style='color:#2F92EE;'>#PDT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13974, encryptionId=73a3139e4e9, topicName=PDT)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e35e25313849, createdName=江川靖瑶, createdTime=Sun Apr 10 03:26:00 CST 2016, time=2016-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1366240, encodeId=806c13662405f, content=<a href='/topic/show?id=186126998e2' target=_blank style='color:#2F92EE;'>#侵袭性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26998, encryptionId=186126998e2, topicName=侵袭性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1be8234, createdName=sunyl07, createdTime=Wed Jul 29 01:26:00 CST 2015, time=2015-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450423, encodeId=6e3d145042366, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Wed Jul 29 01:26:00 CST 2015, time=2015-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1536745, encodeId=453f1536e45bc, content=<a href='/topic/show?id=b38d2e011a6' target=_blank style='color:#2F92EE;'>#侵袭性牙周炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27011, encryptionId=b38d2e011a6, topicName=侵袭性牙周炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26c712719796, createdName=photoman, createdTime=Wed Jul 29 01:26:00 CST 2015, time=2015-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1621546, encodeId=1c8a1621546fb, content=<a href='/topic/show?id=5f1386329e' target=_blank style='color:#2F92EE;'>#Health#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8632, encryptionId=5f1386329e, topicName=Health)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8d2020283215, createdName=yyanpro@28cn.c, createdTime=Wed Jul 29 01:26:00 CST 2015, time=2015-07-29, status=1, ipAttribution=)]
  5. [GetPortalCommentsPageByObjectIdResponse(id=125038, encodeId=714d12503866, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:50:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1861022, encodeId=2be91861022e5, content=<a href='/topic/show?id=401a23e102' target=_blank style='color:#2F92EE;'>#ALT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2371, encryptionId=401a23e102, topicName=ALT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Sat Dec 05 01:26:00 CST 2015, time=2015-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020175, encodeId=7e1220201e5c1, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Thu Jun 02 21:26:00 CST 2016, time=2016-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974617, encodeId=8c6619e461768, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Wed Aug 12 16:26:00 CST 2015, time=2015-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1661516, encodeId=bb67166151625, content=<a href='/topic/show?id=73a3139e4e9' target=_blank style='color:#2F92EE;'>#PDT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13974, encryptionId=73a3139e4e9, topicName=PDT)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e35e25313849, createdName=江川靖瑶, createdTime=Sun Apr 10 03:26:00 CST 2016, time=2016-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1366240, encodeId=806c13662405f, content=<a href='/topic/show?id=186126998e2' target=_blank style='color:#2F92EE;'>#侵袭性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26998, encryptionId=186126998e2, topicName=侵袭性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1be8234, createdName=sunyl07, createdTime=Wed Jul 29 01:26:00 CST 2015, time=2015-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450423, encodeId=6e3d145042366, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Wed Jul 29 01:26:00 CST 2015, time=2015-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1536745, encodeId=453f1536e45bc, content=<a href='/topic/show?id=b38d2e011a6' target=_blank style='color:#2F92EE;'>#侵袭性牙周炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27011, encryptionId=b38d2e011a6, topicName=侵袭性牙周炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26c712719796, createdName=photoman, createdTime=Wed Jul 29 01:26:00 CST 2015, time=2015-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1621546, encodeId=1c8a1621546fb, content=<a href='/topic/show?id=5f1386329e' target=_blank style='color:#2F92EE;'>#Health#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8632, encryptionId=5f1386329e, topicName=Health)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8d2020283215, createdName=yyanpro@28cn.c, createdTime=Wed Jul 29 01:26:00 CST 2015, time=2015-07-29, status=1, ipAttribution=)]
    2016-04-10 江川靖瑶
  6. [GetPortalCommentsPageByObjectIdResponse(id=125038, encodeId=714d12503866, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:50:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1861022, encodeId=2be91861022e5, content=<a href='/topic/show?id=401a23e102' target=_blank style='color:#2F92EE;'>#ALT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2371, encryptionId=401a23e102, topicName=ALT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Sat Dec 05 01:26:00 CST 2015, time=2015-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020175, encodeId=7e1220201e5c1, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Thu Jun 02 21:26:00 CST 2016, time=2016-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974617, encodeId=8c6619e461768, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Wed Aug 12 16:26:00 CST 2015, time=2015-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1661516, encodeId=bb67166151625, content=<a href='/topic/show?id=73a3139e4e9' target=_blank style='color:#2F92EE;'>#PDT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13974, encryptionId=73a3139e4e9, topicName=PDT)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e35e25313849, createdName=江川靖瑶, createdTime=Sun Apr 10 03:26:00 CST 2016, time=2016-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1366240, encodeId=806c13662405f, content=<a href='/topic/show?id=186126998e2' target=_blank style='color:#2F92EE;'>#侵袭性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26998, encryptionId=186126998e2, topicName=侵袭性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1be8234, createdName=sunyl07, createdTime=Wed Jul 29 01:26:00 CST 2015, time=2015-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450423, encodeId=6e3d145042366, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Wed Jul 29 01:26:00 CST 2015, time=2015-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1536745, encodeId=453f1536e45bc, content=<a href='/topic/show?id=b38d2e011a6' target=_blank style='color:#2F92EE;'>#侵袭性牙周炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27011, encryptionId=b38d2e011a6, topicName=侵袭性牙周炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26c712719796, createdName=photoman, createdTime=Wed Jul 29 01:26:00 CST 2015, time=2015-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1621546, encodeId=1c8a1621546fb, content=<a href='/topic/show?id=5f1386329e' target=_blank style='color:#2F92EE;'>#Health#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8632, encryptionId=5f1386329e, topicName=Health)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8d2020283215, createdName=yyanpro@28cn.c, createdTime=Wed Jul 29 01:26:00 CST 2015, time=2015-07-29, status=1, ipAttribution=)]
    2015-07-29 sunyl07
  7. [GetPortalCommentsPageByObjectIdResponse(id=125038, encodeId=714d12503866, content=好文章,还会关注, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Tue Sep 13 11:50:00 CST 2016, time=2016-09-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1861022, encodeId=2be91861022e5, content=<a href='/topic/show?id=401a23e102' target=_blank style='color:#2F92EE;'>#ALT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2371, encryptionId=401a23e102, topicName=ALT)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ccbd84, createdName=shizhenshan, createdTime=Sat Dec 05 01:26:00 CST 2015, time=2015-12-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2020175, encodeId=7e1220201e5c1, content=<a href='/topic/show?id=1584134451c' target=_blank style='color:#2F92EE;'>#Oral#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Thu Jun 02 21:26:00 CST 2016, time=2016-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1974617, encodeId=8c6619e461768, content=<a href='/topic/show?id=f145355379' target=_blank style='color:#2F92EE;'>#BMC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3553, encryptionId=f145355379, topicName=BMC)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/101173734/363C99735735B7F4CB11D5F78F580525/100, createdBy=aab22500211, createdName=ms3025846204744509, createdTime=Wed Aug 12 16:26:00 CST 2015, time=2015-08-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1661516, encodeId=bb67166151625, content=<a href='/topic/show?id=73a3139e4e9' target=_blank style='color:#2F92EE;'>#PDT#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13974, encryptionId=73a3139e4e9, topicName=PDT)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=e35e25313849, createdName=江川靖瑶, createdTime=Sun Apr 10 03:26:00 CST 2016, time=2016-04-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1366240, encodeId=806c13662405f, content=<a href='/topic/show?id=186126998e2' target=_blank style='color:#2F92EE;'>#侵袭性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26998, encryptionId=186126998e2, topicName=侵袭性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1be8234, createdName=sunyl07, createdTime=Wed Jul 29 01:26:00 CST 2015, time=2015-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450423, encodeId=6e3d145042366, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Wed Jul 29 01:26:00 CST 2015, time=2015-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1536745, encodeId=453f1536e45bc, content=<a href='/topic/show?id=b38d2e011a6' target=_blank style='color:#2F92EE;'>#侵袭性牙周炎#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=27011, encryptionId=b38d2e011a6, topicName=侵袭性牙周炎)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=26c712719796, createdName=photoman, createdTime=Wed Jul 29 01:26:00 CST 2015, time=2015-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1621546, encodeId=1c8a1621546fb, content=<a href='/topic/show?id=5f1386329e' target=_blank style='color:#2F92EE;'>#Health#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8632, encryptionId=5f1386329e, topicName=Health)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=8d2020283215, createdName=yyanpro@28cn.c, createdTime=Wed Jul 29 01:26:00 CST 2015, time=2015-07-29, status=1, ipAttribution=)]
  8. 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  9. 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