Am J Otolaryngol:双边突发性感官神经性听力损失注射强的松失败后鼓室内注射地塞米松效果研究

2018-07-29 AlexYang MedSci原创

最近,有研究人员进行了在同时发生的双边突发性感官神经性听力损失中注射强的松治疗失败后,在鼓室内注射地塞米松治疗效果的研究。研究人员对他们所在医院的2007年3月到2018年3月间的同时发生SSNHL案例进行了回顾性的分析。在早期阶段(2007年3月到2012年2月),所有的病理都只进行静脉内注射强的松治疗,并且归到A组。在晚期阶段(2012年2月到2018年3月),在早期阶段治疗失败的患者在鼓室内

最近,有研究人员进行了在同时发生的双边突发性感官神经性听力损失中注射强的松治疗失败后,在鼓室内注射地塞米松治疗效果的研究。

研究人员对他们所在医院的2007年3月到2018年3月间的同时发生SSNHL案例进行了回顾性的分析。在早期阶段(2007年3月到2012年2月),所有的病理都只进行静脉内注射强的松治疗,并且归到A组。在晚期阶段(2012年2月到2018年3月),在早期阶段治疗失败的患者在鼓室内注射地塞米松来治疗同时发生双边SSNHL患者,这些患者归到B组。研究人员对这2种治疗的效果进行了比较。研究发现,在组A,40只耳朵的3只得到了完全的恢复,4只耳朵在静脉注射强的松后得到了部分的恢复,治疗效果比例只占17.5%(7/40)。相比之下,6/44只耳朵在组B中得到完全的恢复,10只耳朵得到了部分的恢复,治疗效果比占36.4%(16/44)。即两组之间存在着显著的治疗效果差异。

最后,研究人员指出,与传统的静脉内注射强的松疗法相比,强的松治疗失败后选择鼓室内注射地塞米松是一种治疗同时发生SSNHL比较好的选择。

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    2018-08-04 liumin1987

    鼓室内注射地塞米松治疗耳部疾病。

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1756794, encodeId=607c1e567942a, content=<a href='/topic/show?id=84065018044' target=_blank style='color:#2F92EE;'>#强的松#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50180, encryptionId=84065018044, topicName=强的松)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee9d37231037, createdName=ms6829001416292975, createdTime=Tue Dec 18 11:39:00 CST 2018, time=2018-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1803461, encodeId=eaff180346150, content=<a href='/topic/show?id=b987e548071' target=_blank style='color:#2F92EE;'>#突发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75480, encryptionId=b987e548071, topicName=突发性)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/L2dMhrxjvSWuPWKZZP1I83Rw21EWia7LVTYJibLQkb4oTibrYLwhnAXntTBWR3FruIzKfNMiaBwhYV0AKNmiaNxfialg/132, createdBy=6ea92500119, createdName=ms9608593228839890, createdTime=Wed Aug 22 17:39:00 CST 2018, time=2018-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2035429, encodeId=c09d203542970, content=<a href='/topic/show?id=d382e42956d' target=_blank style='color:#2F92EE;'>#神经性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74295, encryptionId=d382e42956d, topicName=神经性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=927d310, createdName=hywen7326, createdTime=Thu Jan 24 20:39:00 CST 2019, time=2019-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=336272, encodeId=418b3362e2f8, content=鼓室内注射地塞米松治疗耳部疾病。, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/07/16/3b24606172648eea459125cb74754afe.jpg, createdBy=6c022216608, createdName=liumin1987, createdTime=Sat Aug 04 10:19:56 CST 2018, time=2018-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1306239, encodeId=e4e61306239fb, content=<a href='/topic/show?id=aeb639230b7' target=_blank style='color:#2F92EE;'>#听力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39230, encryptionId=aeb639230b7, topicName=听力)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=96d4340, createdName=ysjykql, createdTime=Tue Jul 31 02:39:00 CST 2018, time=2018-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=334931, encodeId=0578334931c3, content=了解一下,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sun Jul 29 14:44:47 CST 2018, time=2018-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046578, encodeId=0f7e10465e864, content=疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Sun Jul 29 14:39:00 CST 2018, time=2018-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=334921, encodeId=0421334921b6, content=学习了,谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sun Jul 29 13:09:55 CST 2018, time=2018-07-29, status=1, ipAttribution=)]
    2018-07-31 ysjykql
  6. [GetPortalCommentsPageByObjectIdResponse(id=1756794, encodeId=607c1e567942a, content=<a href='/topic/show?id=84065018044' target=_blank style='color:#2F92EE;'>#强的松#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50180, encryptionId=84065018044, topicName=强的松)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee9d37231037, createdName=ms6829001416292975, createdTime=Tue Dec 18 11:39:00 CST 2018, time=2018-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1803461, encodeId=eaff180346150, content=<a href='/topic/show?id=b987e548071' target=_blank style='color:#2F92EE;'>#突发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75480, encryptionId=b987e548071, topicName=突发性)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/L2dMhrxjvSWuPWKZZP1I83Rw21EWia7LVTYJibLQkb4oTibrYLwhnAXntTBWR3FruIzKfNMiaBwhYV0AKNmiaNxfialg/132, createdBy=6ea92500119, createdName=ms9608593228839890, createdTime=Wed Aug 22 17:39:00 CST 2018, time=2018-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2035429, encodeId=c09d203542970, content=<a href='/topic/show?id=d382e42956d' target=_blank style='color:#2F92EE;'>#神经性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74295, encryptionId=d382e42956d, topicName=神经性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=927d310, createdName=hywen7326, createdTime=Thu Jan 24 20:39:00 CST 2019, time=2019-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=336272, encodeId=418b3362e2f8, content=鼓室内注射地塞米松治疗耳部疾病。, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/07/16/3b24606172648eea459125cb74754afe.jpg, createdBy=6c022216608, createdName=liumin1987, createdTime=Sat Aug 04 10:19:56 CST 2018, time=2018-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1306239, encodeId=e4e61306239fb, content=<a href='/topic/show?id=aeb639230b7' target=_blank style='color:#2F92EE;'>#听力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39230, encryptionId=aeb639230b7, topicName=听力)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=96d4340, createdName=ysjykql, createdTime=Tue Jul 31 02:39:00 CST 2018, time=2018-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=334931, encodeId=0578334931c3, content=了解一下,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sun Jul 29 14:44:47 CST 2018, time=2018-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046578, encodeId=0f7e10465e864, content=疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Sun Jul 29 14:39:00 CST 2018, time=2018-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=334921, encodeId=0421334921b6, content=学习了,谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sun Jul 29 13:09:55 CST 2018, time=2018-07-29, status=1, ipAttribution=)]
    2018-07-29 天地飞扬

    了解一下,谢谢分享!

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1756794, encodeId=607c1e567942a, content=<a href='/topic/show?id=84065018044' target=_blank style='color:#2F92EE;'>#强的松#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50180, encryptionId=84065018044, topicName=强的松)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee9d37231037, createdName=ms6829001416292975, createdTime=Tue Dec 18 11:39:00 CST 2018, time=2018-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1803461, encodeId=eaff180346150, content=<a href='/topic/show?id=b987e548071' target=_blank style='color:#2F92EE;'>#突发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75480, encryptionId=b987e548071, topicName=突发性)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/L2dMhrxjvSWuPWKZZP1I83Rw21EWia7LVTYJibLQkb4oTibrYLwhnAXntTBWR3FruIzKfNMiaBwhYV0AKNmiaNxfialg/132, createdBy=6ea92500119, createdName=ms9608593228839890, createdTime=Wed Aug 22 17:39:00 CST 2018, time=2018-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2035429, encodeId=c09d203542970, content=<a href='/topic/show?id=d382e42956d' target=_blank style='color:#2F92EE;'>#神经性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74295, encryptionId=d382e42956d, topicName=神经性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=927d310, createdName=hywen7326, createdTime=Thu Jan 24 20:39:00 CST 2019, time=2019-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=336272, encodeId=418b3362e2f8, content=鼓室内注射地塞米松治疗耳部疾病。, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/07/16/3b24606172648eea459125cb74754afe.jpg, createdBy=6c022216608, createdName=liumin1987, createdTime=Sat Aug 04 10:19:56 CST 2018, time=2018-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1306239, encodeId=e4e61306239fb, content=<a href='/topic/show?id=aeb639230b7' target=_blank style='color:#2F92EE;'>#听力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39230, encryptionId=aeb639230b7, topicName=听力)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=96d4340, createdName=ysjykql, createdTime=Tue Jul 31 02:39:00 CST 2018, time=2018-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=334931, encodeId=0578334931c3, content=了解一下,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sun Jul 29 14:44:47 CST 2018, time=2018-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046578, encodeId=0f7e10465e864, content=疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Sun Jul 29 14:39:00 CST 2018, time=2018-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=334921, encodeId=0421334921b6, content=学习了,谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sun Jul 29 13:09:55 CST 2018, time=2018-07-29, status=1, ipAttribution=)]
    2018-07-29 CHANGE

    疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1756794, encodeId=607c1e567942a, content=<a href='/topic/show?id=84065018044' target=_blank style='color:#2F92EE;'>#强的松#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50180, encryptionId=84065018044, topicName=强的松)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee9d37231037, createdName=ms6829001416292975, createdTime=Tue Dec 18 11:39:00 CST 2018, time=2018-12-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1803461, encodeId=eaff180346150, content=<a href='/topic/show?id=b987e548071' target=_blank style='color:#2F92EE;'>#突发性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=46, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=75480, encryptionId=b987e548071, topicName=突发性)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/L2dMhrxjvSWuPWKZZP1I83Rw21EWia7LVTYJibLQkb4oTibrYLwhnAXntTBWR3FruIzKfNMiaBwhYV0AKNmiaNxfialg/132, createdBy=6ea92500119, createdName=ms9608593228839890, createdTime=Wed Aug 22 17:39:00 CST 2018, time=2018-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2035429, encodeId=c09d203542970, content=<a href='/topic/show?id=d382e42956d' target=_blank style='color:#2F92EE;'>#神经性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74295, encryptionId=d382e42956d, topicName=神经性)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=927d310, createdName=hywen7326, createdTime=Thu Jan 24 20:39:00 CST 2019, time=2019-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=336272, encodeId=418b3362e2f8, content=鼓室内注射地塞米松治疗耳部疾病。, beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/07/16/3b24606172648eea459125cb74754afe.jpg, createdBy=6c022216608, createdName=liumin1987, createdTime=Sat Aug 04 10:19:56 CST 2018, time=2018-08-04, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1306239, encodeId=e4e61306239fb, content=<a href='/topic/show?id=aeb639230b7' target=_blank style='color:#2F92EE;'>#听力#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39230, encryptionId=aeb639230b7, topicName=听力)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=96d4340, createdName=ysjykql, createdTime=Tue Jul 31 02:39:00 CST 2018, time=2018-07-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=334931, encodeId=0578334931c3, content=了解一下,谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2019/12/23/2f51002e1349ccda5be11c1eea1e1e60.jpg, createdBy=a22097948, createdName=天地飞扬, createdTime=Sun Jul 29 14:44:47 CST 2018, time=2018-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1046578, encodeId=0f7e10465e864, content=疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=CHANGE, createdTime=Sun Jul 29 14:39:00 CST 2018, time=2018-07-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=334921, encodeId=0421334921b6, content=学习了,谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Sun Jul 29 13:09:55 CST 2018, time=2018-07-29, status=1, ipAttribution=)]
    2018-07-29 惠映实验室

    学习了,谢谢分享。

    0

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在具有功能性残余低频听力的患者中,为了引起内耳结构最小的创伤,需要根据已经建立的听力保留外科手术技术进行耳蜗移植。由于在儿童中耳蜗移植的数目在不断增加,参与听力的保留情况在该病人群体中越来越重要。最近,有研究人员调查了儿科患者中短期和中期听力保留情况。研究包括了9名儿童(12只耳朵),年龄在5岁到12岁之间。研究人员调查了耳蜗移植后的纯音听觉阈值情况。研究人员调查了短期听力保留(术后最多3个月)情

Sci Rep:恰克-马利-杜斯氏症第1A型患者隐性听力损失研究

最近,有研究人员调查了患有恰克-马利-杜斯氏症第1A型(CMT1A)患者的隐性听力损失情况。CMT1A是一种常见的遗传性脱髓鞘性神经病。研究人员通过使用纯音听觉调查,筛选出了43名患有CMT1A的患者和60名具有正常声音检测能力的健康对照。研究人员测量了在安静和噪音背景下的言语感知、光谱波纹鉴别(SRD)和时间调制检测(TMD)。研究发现,尽管CMT1A患者和健康对照具有相似的纯音听觉阈值和在安静

PLoS One:脚趾甲中砷水平与听力损失相关

饮用水中的砷(As)污染是世界范围内人类健康的风险因子。研究人员之前展示了居住在饮用水As污染地区的年轻人存在听力损失情况,且在As处理的年轻小鼠中也存在听力损失情况。最近,有研究人员利用流行病学方法,在2014年调查了145名孟加拉国且年龄在12-55岁参与者中脚趾甲As水平与听力之间的相关性。调整年龄、星币、抽烟和BMI后,利用多变量分析研究发现,脚趾甲中As中的水平(而不是尿液)与听力损失在