Eur Heart J:心血管疾病妇女的妊娠结局

2019-04-01 xing.T 网络

由此可见,心脏病女性的孕产妇死亡率或心力衰竭率很高。然而,从2010年开始,尽管包含更多高风险妊娠,但这些发生率仍然下降。PAH女性的并发症发生率最高。

降低孕产妇死亡率是世界卫生组织(WHO)的全球健康目标。虽然由于出血和感染引起的孕产妇死亡率正在下降,但与心脏病有关的死亡人数正在增加,并且成为了西方国家最重要的原因。近日,血管领域权威杂志Eur Heart J上发表了一篇研究文章,该研究旨在明确心脏病孕妇的特定结局。

从2007年到2018年,患有心脏病的孕妇被前瞻性地纳入了妊娠和心脏病登记处(ROPAC)。该研究的主要结局是孕产妇死亡率或心力衰竭,次要结局是其他心脏、产科和胎儿并发症。

研究人员招募了5739名孕妇;平均年龄为29.5岁。较为常见的诊断为先天性心脏病(57%)和心脏瓣膜病(29%)。肺动脉高压(PAH)组的死亡率(总体0.6%)最高(9%)。心力衰竭发生率为11%,心律失常发生率为2%。剖腹产分娩率为44%。产科和胎儿并发症分别发生在17%和21%。高危妊娠(mWHO IV级)的数量从2007-2010年期间的0.7%增加到2015-2018年期间的10.9%。产妇并发症的决定因素是妊娠前心力衰竭或纽约心功能分级>II,全身射血分数<40%,mWHO 4级和使用抗凝血剂。从2007年到2009年增加后,并发症发生率从2010年的13.2%下降到2017年的9.3%。

由此可见,心脏病女性的孕产妇死亡率或心力衰竭率很高。然而,从2010年开始,尽管包含更多高风险妊娠,但这些发生率仍然下降。PAH女性的并发症发生率最高。

原始出处:

Jolien Roos-Hesselink.et al.Pregnancy outcomes in women with cardiovascular disease: evolving trends over 10 years in the ESC Registry Of Pregnancy And Cardiac disease (ROPAC).Eur Heart J.https://doi.org/10.1093/eurheartj/ehz136

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    2019-04-03 zhaojie88
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    2019-04-03 slcumt
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    2019-04-01 1209e435m98(暂无昵称)

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