SCI REP:胃腺鳞癌的临床病理特征及预后!

2017-07-04 xing.T MedSci原创

由此可见,胃部ASC与AC在临床病理特征上具有明显的不同,并且胃部ASC的预后要明显差于AC。

由于原发性胃腺鳞癌(ASC)罕见的发病率,关于ASC的数据是有限的。近日,Scientific reports 杂志上发表了一篇研究文章,该研究旨在调查胃部ASC的临床病理特征和预后。

胃部ASC病例来自于研究人员所在的医疗中心以及从Medline数据库中提取出的病例报告和病例系列。研究人员分析了胃部ASC的临床病理特征和预后,并将其与研究人员所在医疗中心的胃腺癌(AC)病例进行比较。

研究人员发现胃部ASC最常见的位置是胃部下三分之一(45.0%),其次是上三分之一(26.2%)然后是中部三分之一(24.2%)。中位肿瘤大小为6厘米(0.8-17)。 ASC最常见的分化状态同时有AC(44.4%)和SCC成分(40.9%)。一半的肿瘤患者(52.7%)为T4期,大多数ASC患者(86.2%)患有淋巴结转移(LNM)。肿瘤深度和TNM分期是ASC患者总生存期(OS)的危险因素(所有P<0.05)。胃部ASC和AC患者之间在年龄、肿瘤大小、肿瘤位置、肿瘤深度、LNM和TNM分期的分布上具有显著的差异(所有P<0.05)。而且,研究人员发现胃部ASC患者的OS明显低于AC患者(P<0.001),特别是在III期疾病的患者中(P<0.001)。

由此可见,胃部ASC与AC在临床病理特征上具有明显的不同,并且胃部ASC的预后要明显差于AC。

原始出处:

Fan Feng, et al. Clinicopathological features and prognosis of gastric adenosquamous carcinoma.Scientific reports. 2017. https://www.nature.com/articles/s41598-017-04563-2

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    2017-08-06 1e0cdf4em36(暂无匿称)

    学习了并分享

    0

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    2017-07-06 changjiu

    学习了谢谢

    0

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  6. [GetPortalCommentsPageByObjectIdResponse(id=2033192, encodeId=e57f2033192a7, content=<a href='/topic/show?id=c097e104497' target=_blank style='color:#2F92EE;'>#病理特征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71044, encryptionId=c097e104497, topicName=病理特征)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c279140, createdName=vividelife, createdTime=Sat Sep 02 15:04:00 CST 2017, time=2017-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1797464, encodeId=32d31e9746451, content=<a href='/topic/show?id=96eb22906b9' target=_blank style='color:#2F92EE;'>#临床病理#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22906, encryptionId=96eb22906b9, topicName=临床病理)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Wed Apr 11 11:04:00 CST 2018, time=2018-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=230550, encodeId=ed1423055073, content=学习了并分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuK7MtpefUjs5gdyd9SPjFgf48Ev1UPCfuRGKO8dL46bCN6ynydTWnVZjOk6KvWloBvRbiatjYgMag/0, createdBy=4f2b1931429, createdName=1e0cdf4em36(暂无匿称), createdTime=Sun Aug 06 07:05:12 CST 2017, time=2017-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=219241, encodeId=e02f2192414f, content=学习了谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Thu Jul 06 20:06:16 CST 2017, time=2017-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1484633, encodeId=208b14846330e, content=<a href='/topic/show?id=3502102944e7' target=_blank style='color:#2F92EE;'>#鳞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102944, encryptionId=3502102944e7, topicName=鳞癌)], attachment=null, authenticateStatus=null, createdAvatar=Bioon/avatar/20171006/a73877485ccdf6add82293e671bebe21.jpg, createdBy=745a7977375, createdName=1696533704_45270456, createdTime=Thu Jul 06 11:04:00 CST 2017, time=2017-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218734, encodeId=6c53218e3453, content=学习了谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aadd1680584, createdName=蔬菜, createdTime=Wed Jul 05 08:12:07 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218670, encodeId=22cd2186e090, content=学习了谢谢分享!!:, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Wed Jul 05 06:25:40 CST 2017, time=2017-07-05, status=1, ipAttribution=)]
    2017-07-05 蔬菜

    学习了谢谢分享!

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=2033192, encodeId=e57f2033192a7, content=<a href='/topic/show?id=c097e104497' target=_blank style='color:#2F92EE;'>#病理特征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71044, encryptionId=c097e104497, topicName=病理特征)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c279140, createdName=vividelife, createdTime=Sat Sep 02 15:04:00 CST 2017, time=2017-09-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1797464, encodeId=32d31e9746451, content=<a href='/topic/show?id=96eb22906b9' target=_blank style='color:#2F92EE;'>#临床病理#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22906, encryptionId=96eb22906b9, topicName=临床病理)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c689267, createdName=cmj8wellington, createdTime=Wed Apr 11 11:04:00 CST 2018, time=2018-04-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=230550, encodeId=ed1423055073, content=学习了并分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuK7MtpefUjs5gdyd9SPjFgf48Ev1UPCfuRGKO8dL46bCN6ynydTWnVZjOk6KvWloBvRbiatjYgMag/0, createdBy=4f2b1931429, createdName=1e0cdf4em36(暂无匿称), createdTime=Sun Aug 06 07:05:12 CST 2017, time=2017-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=219241, encodeId=e02f2192414f, content=学习了谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLGSUSR8zwnWWLT4FMl5XH8S58HuZslVkLsAPbXDXaliagK7TOxQfmngKibG1yrDonepCLDkcxGk8hS/0, createdBy=b8282062892, createdName=changjiu, createdTime=Thu Jul 06 20:06:16 CST 2017, time=2017-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1484633, encodeId=208b14846330e, content=<a href='/topic/show?id=3502102944e7' target=_blank style='color:#2F92EE;'>#鳞癌#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102944, encryptionId=3502102944e7, topicName=鳞癌)], attachment=null, authenticateStatus=null, createdAvatar=Bioon/avatar/20171006/a73877485ccdf6add82293e671bebe21.jpg, createdBy=745a7977375, createdName=1696533704_45270456, createdTime=Thu Jul 06 11:04:00 CST 2017, time=2017-07-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218734, encodeId=6c53218e3453, content=学习了谢谢分享!, beContent=null, objectType=article, channel=null, level=null, likeNumber=58, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=aadd1680584, createdName=蔬菜, createdTime=Wed Jul 05 08:12:07 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=218670, encodeId=22cd2186e090, content=学习了谢谢分享!!:, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20200816/e4675a86ea694f12b82202b320dc2654/12f6b900498349e994ce8f516a584d6a.jpg, createdBy=09431951290, createdName=大爰, createdTime=Wed Jul 05 06:25:40 CST 2017, time=2017-07-05, status=1, ipAttribution=)]
    2017-07-05 大爰

    学习了谢谢分享!!:

    0