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Radiology：扫个磁共振患者老是动怎么办？

2017-11-15 shaosai MedSci原创

轻度认知障碍帕金森病磁共振波谱
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本研究旨在轻度认知障碍（MCI）、帕金森病（PD）和中老年健康志愿者进行实时校正3Dγ氨基丁酸MR波谱成像中比较不可抗拒头部运动、频率及B0变化、对数据质量的影响，并将结果发表在Radiology上。

本研究旨在轻度认知障碍（MCI）、帕金森病（PD）和中老年健康志愿者进行实时校正3Dγ氨基丁酸MR波谱成像中比较不可抗拒头部运动、频率及B0变化、对数据质量的影响，并将结果发表在Radiology上。

本研究采用3T磁共振进行成像，利用整合体积导航评价头部平面及旋转运动、频率及B0变化。共对33年轻健康志愿者、34名老年健康志愿者、34例MCI患者及44例PD患者的头部运动模式及成像不稳定情况进行研究。利用ROI分析评价波谱质量。利用Bonferroni校正Mann-Whitney U检验评价组间差异。

由于头部运动过大，3例PD患者和4例MCI患者被排除（如在总扫描时间＞10分钟中每次重复时间＞1.6秒时运动超过0.8mm）。与相比，年老对照组、PD患者、MCI患者出现头部运动幅度要比年轻对照组(1.79 mm ± 0.77) (P < .001)分别严重1.5、2、2.5倍。在MR波谱成像采集超过20分钟时，约有6%的年轻志愿者、35%的老年志愿者、38%的PD患者和51%的MCI患者头部运动超过3mm。主要的动作为点头和 "滑出"。PD患者(P = .007)和MCI患者(P < .001)的频率改变分别是年轻对照组的1.1、1.4倍；老年对照组(P = .005)、PD患者(P < .001)和MCI患者(P < .001)B0改变分别是年轻对照组(12.59 Hz ± 2.49， 3.61 Hz · cm -1 ± 1.25)的1.3、1.5、1.9倍。在4组实时校正表现出较高的波普质量。（信噪比＞15，Cramér-Rao lower bounds < 20%）。

本研究表明，实时运动和B0检查能够提供运动模式和B0场强变异的有用信息。实时校正提高了数据质量，尤其是对于无法制动的患者。

原始出处：

Heckova E， Pova？an M， Strasser B. et al.Real-time Correction of Motion and Imager Instability Artifacts during 3D γ-Aminobutyric Acid-edited MR Spectroscopic Imaging.Radiology.DOI： 10.1148/radiol.2017170744

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    2017-11-27 虈亣靌

    讲解的非常好,值得学习

    0

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    2017-11-17 1696533704_45270454

    #磁共振#

    0

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    2017-11-16 虈亣靌

    学习一下很不错

    0

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    2017-11-15 1ddf0692m34(暂无匿称)

    学习了.好文章

    0

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    2017-11-15 有备才能无患

    本研究旨在轻度认知障碍(MCI).帕金森病(PD)和中老年健康志愿者进行实时校正3Dγ氨基丁酸MR波谱成像中比较不可抗拒头部运动.频率及B0变化.对数据质量的影响.并将结果发表在Radiology上.

    0

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