Obesity Reviews:中国青少年糖尿病发病率约是美国同龄人的四倍

2012-07-16 MedSci MedSci原创

一项来自北卡罗来纳大学教堂山分校研究人员的研究发现,中国青少年的糖尿病发病率约是美国同龄青少年的四倍多。中国越来越多的超重人群导致了糖尿病发病率的上升。 这项研究由Barry Popkin博士——北卡大学吉林斯全球公共健康学院的“W.R. Kenan Jr. 杰出教授”荣誉获得者——-和中国研究人员共同完成,数据资料来自中国健康和营养调查研究。在1989-2011年间,这项研究的实施者在中国3

一项来自北卡罗来纳大学教堂山分校研究人员的研究发现,中国青少年的糖尿病发病率约是美国同龄青少年的四倍多。中国越来越多的超重人群导致了糖尿病发病率的上升。



这项研究由Barry Popkin博士——北卡大学吉林斯全球公共健康学院的“W.R. Kenan Jr. 杰出教授”荣誉获得者——-和中国研究人员共同完成,数据资料来自中国健康和营养调查研究。在1989-2011年间,这项研究的实施者在中国300个社区随访超过29000人并且分别在1989, 1991, 1993, 1997, 2000, 2004, 2006, 2009 和 2011年开展调查研究。中国健康和营养调查项目是由北卡罗来纳大学教堂山分校和中国疾控中心营养与食品安全研究所合作开展的。

这项研究成果在线刊登在Obesity Reviews杂志的Early View专栏,并将发表在2012年Obesity Reviews杂志第13卷第九期上。

中国在过去二十年经历了前所未有的经济增长,但本研究同时发现,中国人同时也经历着体重、饮食和体力活动水平方面的剧烈变化。2009年,北卡大学和中国疾控中心研究人员对随机抽选的代表56%中国人群的样本的随访发现,国人的超重和心血管危险因素大幅增加。

“令人惊讶的是七岁及七岁以上儿童在饮食、体重及心血管风险方面的变化。” “评估(报告)表明:“如果这种情况没有发生任何改变,中国的医疗保健体系将面临巨大的负担。”

北卡大学和中国疾控中心团队观察到7-17岁中国青少年糖尿病的发病率为1.9%;糖尿病前期为14.9%。研究人员也注意到青少年血液中糖化血红蛋白处于较高水平-HbA1c是反应过去两三个月血浆中血糖的平均水平的指标。

“这些研究结果表明从年轻时开始慢性疾病风险的负担就已经很高,在7-18岁中国青少年中间约有170万糖尿病患者和2770万糖尿病前期患者” Popkin说。“此外,在18岁以下中国青少年中,有超过三分之一的青少年至少有一个心血管代谢风险因素处于高水平。”。成人中,中国约有3.34亿糖尿病前期或糖尿病患者。

与来自中国的数据资料相比,来自美国的数据资料(基于国家健康和营养调查的结果)表明,中国青少年人群糖尿病和炎症发生率要高于美国同龄人,也高于其他一些亚洲国家。研究人员发现12-18岁的中国青少年人群糖尿病的发病率为1.9%,而美国同龄人只有0.5%。研究同时发现炎症-一个重要的心血管风险因子 -的发生率在两国青少年也有显著差异:在中国青少年为12.1%,而在美国青少年只有8.5%。

“在40岁及40岁以上人群,至少有一个心血管危险因素处于较高水平的比例提高到了85%”, 北卡大学吉林斯全球公共健康学院营养学教授,Penny Gordon-Larsen博士说到,“更令人担忧的是,这些有较高风险的人遍布于整个国家:无论在农村、城市;还是高收入者、低收入者。因此,将来产生的医疗费用和影响是巨大的”。

这些研究结果印证了以前的研究发现:即在过去十年,中国低收入人群及农村人群也开始出现了越来越多的肥胖患者。

原始链接:

S. Yan, J. Li, S. Li, B. Zhang, S. Du, P. Gordon-Larsen, L. Adair and B. Popkin. The expanding burden of cardiometabolic risk in China: the China Health and Nutrition Survey Article first published online: 28 JUN 2012 | DOI: 10.1111/j.1467-789X.2012.01016.x

China faces a major increase in cardiovascular disease, yet there is limited population-based data on risk factors, particularly in children. Fasting blood samples, anthropometry and blood pressure were collected on 9,244 children and adults aged ≥7 years in late 2009 as part of the national China Health and Nutrition Survey. Prevalent overweight, elevated blood pressure, and cardiometabolic risk factors: glucose, HbA1c, triglycerides (TG), total cholesterol (TC), high- and low-density lipoprotein cholesterol (HDL-C and LDL-C), and C-reactive protein (CRP) are presented. We found that 11% of Chinese children and 30% of Chinese adults are overweight. Rates of diabetes, dyslipidaemia, hypertension and inflammation are high and increased with age and were associated with urbanization. Approximately 42% of children have at least one of the following: pre-diabetes or diabetes, hypertension, high TC, LDL-C, TG, and CRP and low HDL-C, as do 70% men and 60% women aged 18–40 years and >90% of men and women ≥60 years. In sum, the HbA1c findings suggest that as many as 27.7 million Chinese children and 334 million Chinese adults may be pre-diabetic or diabetic. The high prevalence in less urban areas and across all income levels suggests that cardiometabolic risk is pervasive across rural and urban China.

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    2013-02-14 智慧医人
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    2012-12-05 xugumin
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    2012-07-18 lingaifan
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    2012-07-18 zhouqu_8

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