Heart:震惊!年轻吸烟者急性ST段抬高心梗风险显著上升

2017-05-27 吴星 环球医学

2017年4月,发表在《Heart》的一项由英国科学家进行的研究表明,年轻吸烟者急性ST段抬高心梗风险显著上升。

2017年4月,发表在《Heart》的一项由英国科学家进行的研究表明,年轻吸烟者急性ST段抬高心梗风险显着上升。

目的:既往研究显现,吸烟者出现ST段抬高心梗(STEMI)的时间比非吸烟者早十年。然而,尚无吸烟人群趋势的报道,该研究弥补了这一不足。

方法:分析国家统计局提供的关于南约克郡2009年至2012年行经皮冠状动脉介入治疗的急性STEMI患者的入院和人口统计学联合数据,量化整体及不同年龄亚组吸烟相关STEMI相对风险,包括发病率和比率(RR)。

结果:纳入1795例STEMI患者,72.9%为男性。排除68例没有吸烟记录的患者,其余48.5%的人群为目前吸烟者,27.2%为既往吸烟者,24.3%为从未吸烟者。吸烟者的比例超过南约克郡的整体吸烟率22.4%。年龄低于50岁、50~65岁以及超过65岁的吸烟者的STEMI发生率分别为59.7、316.9和331.0每100000患者-年,相比之下,既往吸烟者和从未吸烟者的STEMI发生率分别为7.0、60.9和106.8。与同年龄不吸烟者相比,年龄在50岁以下者的发生率增加8.47(95% CI 6.80~10.54),年龄在50~65岁和65岁以上人群的RRs分别为5.20(95% CI 4.76~5.69)和3.10(95% CI 2.67~3.60)。

结论与既往吸烟者和从未吸烟者相比,年轻吸烟者吸烟与急性ST段抬高心梗风险增加8倍相关。

原始出处:

Lloyd A, Steele L, Fotheringham J, et al. Pronounced increase in risk of acute ST-segment elevation myocardial infarction in younger smokers.Heart. 2017 Apr;103(8):586-591. doi: 10.1136/heartjnl-2016-309595. Epub 2016 Nov 29.

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    2017-05-29 zhaojie88
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    2017-05-29 gdsun
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    2017-05-29 slcumt
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    2017-05-29 hyf035
  7. [GetPortalCommentsPageByObjectIdResponse(id=2016083, encodeId=3e412016083cb, content=<a href='/topic/show?id=1f5a510e731' target=_blank style='color:#2F92EE;'>#心梗风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51077, encryptionId=1f5a510e731, topicName=心梗风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=63a4277, createdName=cy0324, createdTime=Mon Jul 24 02:45:00 CST 2017, time=2017-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356284, encodeId=fff11356284b9, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Mon May 29 00:45:00 CST 2017, time=2017-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1423025, encodeId=39ac142302503, content=<a href='/topic/show?id=936c16863b5' target=_blank style='color:#2F92EE;'>#ST段抬高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16863, encryptionId=936c16863b5, topicName=ST段抬高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=91d33758978, createdName=gdsun, createdTime=Mon May 29 00:45:00 CST 2017, time=2017-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562537, encodeId=1e5c156253e11, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Mon May 29 00:45:00 CST 2017, time=2017-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1605107, encodeId=f771160510e7e, content=<a href='/topic/show?id=5cba39435fd' target=_blank style='color:#2F92EE;'>#吸烟者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39435, encryptionId=5cba39435fd, topicName=吸烟者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cc8619318136, createdName=124984e7m89暂无昵称, createdTime=Mon May 29 00:45:00 CST 2017, time=2017-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624349, encodeId=e535162434949, content=<a href='/topic/show?id=f27b16862d9' target=_blank style='color:#2F92EE;'>#ST段#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16862, encryptionId=f27b16862d9, topicName=ST段)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=676820671866, createdName=hyf035, createdTime=Mon May 29 00:45:00 CST 2017, time=2017-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=203199, encodeId=304f20319946, content=学习了,又涨知识了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Sat May 27 11:19:24 CST 2017, time=2017-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=203187, encodeId=dd5420318edd, content=好文章学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Sat May 27 10:35:24 CST 2017, time=2017-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=203178, encodeId=c2762031e8ce, content=好好学习,感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib2cQVB0w6wKXcuEC4Enl0NTBvgHc6yoUM80A3TDia90Fo2MPicibnfm59eh7A0WoicrZXI2hde9ctxKPrlXhzNdL6oZ/0, createdBy=27371624227, createdName=zhangqingzui, createdTime=Sat May 27 10:05:45 CST 2017, time=2017-05-27, status=1, ipAttribution=)]
    2017-05-27 明天会更好!

    学习了,又涨知识了!

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=2016083, encodeId=3e412016083cb, content=<a href='/topic/show?id=1f5a510e731' target=_blank style='color:#2F92EE;'>#心梗风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51077, encryptionId=1f5a510e731, topicName=心梗风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=63a4277, createdName=cy0324, createdTime=Mon Jul 24 02:45:00 CST 2017, time=2017-07-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1356284, encodeId=fff11356284b9, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Mon May 29 00:45:00 CST 2017, time=2017-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1423025, encodeId=39ac142302503, content=<a href='/topic/show?id=936c16863b5' target=_blank style='color:#2F92EE;'>#ST段抬高#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16863, encryptionId=936c16863b5, topicName=ST段抬高)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=91d33758978, createdName=gdsun, createdTime=Mon May 29 00:45:00 CST 2017, time=2017-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1562537, encodeId=1e5c156253e11, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Mon May 29 00:45:00 CST 2017, time=2017-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1605107, encodeId=f771160510e7e, content=<a href='/topic/show?id=5cba39435fd' target=_blank style='color:#2F92EE;'>#吸烟者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39435, encryptionId=5cba39435fd, topicName=吸烟者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cc8619318136, createdName=124984e7m89暂无昵称, createdTime=Mon May 29 00:45:00 CST 2017, time=2017-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1624349, encodeId=e535162434949, content=<a href='/topic/show?id=f27b16862d9' target=_blank style='color:#2F92EE;'>#ST段#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=16862, encryptionId=f27b16862d9, topicName=ST段)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=676820671866, createdName=hyf035, createdTime=Mon May 29 00:45:00 CST 2017, time=2017-05-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=203199, encodeId=304f20319946, content=学习了,又涨知识了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20160914/IMG57D82E721DB581755.jpg, createdBy=4fc81933929, createdName=明天会更好!, createdTime=Sat May 27 11:19:24 CST 2017, time=2017-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=203187, encodeId=dd5420318edd, content=好文章学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Sat May 27 10:35:24 CST 2017, time=2017-05-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=203178, encodeId=c2762031e8ce, content=好好学习,感谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib2cQVB0w6wKXcuEC4Enl0NTBvgHc6yoUM80A3TDia90Fo2MPicibnfm59eh7A0WoicrZXI2hde9ctxKPrlXhzNdL6oZ/0, createdBy=27371624227, createdName=zhangqingzui, createdTime=Sat May 27 10:05:45 CST 2017, time=2017-05-27, status=1, ipAttribution=)]
    2017-05-27 139****5926

    好文章学习了

    0

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    2017-05-27 zhangqingzui

    好好学习,感谢分享

    0

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Int J Cancer:饮酒和吸烟可增加对侧乳腺癌风险!

饮酒和吸烟是第一原发性乳腺癌的危险因素。临床诊断时,这些信息可能有助于对侧乳腺癌(CBC)的风险预测,同时他们也是潜在地可变因子。WECARE研究是一个对乳腺癌女性进行的以人群为基础的病例对照研究,该研究中有不同期的CBC女性(n = 1521)和对照组(n = 2212),对比了二组间的生存时间及其它因素、患有单侧乳腺癌(UBC)。本研究的研究人员研究了在第一次诊断时和诊断之后,与饮酒史和吸烟史

ATS2017:即使无COPD,吸烟者仍然面临着较高的死亡风险!

在一项新的研究中,CT测量的血管修剪——远端肺血管(肺外缘血管)的减少与没有慢性阻塞性肺疾病(COPD)的吸烟者的死亡风险增加相关。该研究在2017年美国胸科协会国际会议上提出。

AIM:年轻人心血管疾病风险升高情况如何?大数据横断面研究告诉你

背景:美国心脏病学会和美国心脏学会(ACC/AHA) 的2013胆固醇管理指南推荐在所有20岁以上的成人中进行血脂筛查来识别动脉粥样硬化性心血管疾病(ASCVD)风险的增加。他汀类药物可被用于10年风险较高者(>5%) 或低密度脂蛋白胆固醇(LDL-C)水平≥4.92 mmol/L (190 mg/dL) 的患者。目的:本研究的目的是描述在小于50岁的非糖尿病成人中,心血管疾病风险升高的发生

Circulation:迄今为止大规模的冠心病「基因-吸烟」研究显示,吸烟简直就是作死

宾夕法尼亚大学的研究人员开展了一项涉及14.1万人的研究,终于找到了基因学证据来解释吸烟是如何导致冠心病的。吸烟会增加一种酶的产生,而这种酶会促进冠状动脉脂肪斑块的积聚,从而增加冠心病的患病风险[1]!

ATS 2017:吸烟者请注意:身体发生这一变化很可能是致命的!

吸烟会导致多种疾病。新的研究表明,胸部肌肉量越少,由于吸烟导致的死亡风险越高。来自疾病控制和预防中心(CDC)报告表示,吸烟是可预防疾病和死亡的第一大原因,