Intens Care Med:经胸超声心动图与脓毒症死亡率!

2018-06-05 xing.T MedSci原创

由此可见,在脓毒症危重患者中,接受TTE检查与28天死亡率的改善有关。

虽然经胸超声心动图(TTE)在ICU中的使用正在迅速推广,但是TTE改变能否改善ICU败血症患者结局的能力还没有被评估。近日,危重病医学领域权威杂志Intensive Care Medicine上发表了一篇研究文章,该研究旨在评估这群患者TTE与28天死亡率之间的关联。

研究人员使用MIMIC-III数据库来确定接受或没有接受TTE检查的脓毒症患者。所采用的统计方法包括多元回归、倾向评分分析、双稳健估计、梯度提升模型和逆概率加权模型,以确保该研究结果的稳健性。

与对照组相比,接受TTE检查的患者28天死亡率显著改善(比值比=0.78,95%可信区间为0.68-0.90,P<0.001)。接受TTE检查的患者液体给药量(第1天: 2.5 vs. 2.1L,P<0.001)、多巴酚丁胺给药量(2% vs. 1%,P=0.007)、去甲肾上腺素的最大剂量(1.4 vs. 1mg/min,P=0.001)明显增加。更重要的是,接受TTE检查的患者停掉血管升压剂比未接受TTE检查的患者(28天中血管紧张素停用为第21天 vs. 第19天,P=0.004)更快。

由此可见,在脓毒症危重患者中,接受TTE检查与28天死亡率的改善有关。

原始出处:

Mengling Feng, et al. Transthoracic echocardiography and mortality in sepsis: analysis of the MIMIC-III database.Intensive Care Medicine.2018. http://icmjournal.esicm.org/journals/abstract.html?v=0&j=134&i=0&a=5208_10.1007_s00134-018-5208-7&doi=

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    2018-06-10 1dd8c52fm63(暂无匿称)

    学习学习.了解了解

    0

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  6. [GetPortalCommentsPageByObjectIdResponse(id=1706530, encodeId=88ce1e065306c, content=<a href='/topic/show?id=3530e8462f9' target=_blank style='color:#2F92EE;'>#经胸超声心动图#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=78462, encryptionId=3530e8462f9, topicName=经胸超声心动图)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=92ab31287727, createdName=12498561m42(暂无昵称), createdTime=Wed Feb 06 12:00:00 CST 2019, time=2019-02-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1651042, encodeId=62a716510423a, content=<a href='/topic/show?id=2aa35090181' target=_blank style='color:#2F92EE;'>#心动图#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=50901, encryptionId=2aa35090181, topicName=心动图)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智慧医人, createdTime=Sun Feb 10 13:00:00 CST 2019, time=2019-02-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2038912, encodeId=dcf12038912a3, content=<a href='/topic/show?id=b45d1e274e8' target=_blank style='color:#2F92EE;'>#TENS#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17274, encryptionId=b45d1e274e8, topicName=TENS)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=3b172500206, createdName=12498ebem19暂无昵称, createdTime=Wed Oct 17 09:00:00 CST 2018, time=2018-10-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=322987, encodeId=de7532298ee4, content=学习学习.了解了解, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=93f31631454, createdName=1dd8c52fm63(暂无匿称), createdTime=Sun Jun 10 08:01:05 CST 2018, time=2018-06-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1608863, encodeId=453b16088638d, content=<a href='/topic/show?id=eb6b1145939' target=_blank style='color:#2F92EE;'>#Med#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11459, encryptionId=eb6b1145939, topicName=Med)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=552a19396740, createdName=ms3994565386320060, createdTime=Thu Jun 07 12:00:00 CST 2018, time=2018-06-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=321950, encodeId=45ce32195049, content=内容与结论有悖, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170701/IMG595791009FB761316.jpg, createdBy=abd01695121, createdName=吴教授, createdTime=Wed Jun 06 14:17:13 CST 2018, time=2018-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=321857, encodeId=d5a432185ee5, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Wed Jun 06 07:31:29 CST 2018, time=2018-06-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=321856, encodeId=3b0132185650, content=好文献学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=b5a62240667, createdName=张新亮1853311252142e2fm, createdTime=Wed Jun 06 07:30:26 CST 2018, time=2018-06-06, status=1, ipAttribution=)]
    2018-06-06 吴教授

    内容与结论有悖

    0

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    2018-06-06 张新亮1853311252142e2fm

    好文献学习了

    0

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    2018-06-06 张新亮1853311252142e2fm

    好文献学习了

    0

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