BMJ: 胃排空速度加快能够改善肥胖患者抽吸治疗的效果

2019-09-13 不详 MedSci原创

吸入治疗(AT)对肥胖的有效性依赖于餐后的最佳抽吸时间,其可以根据患者的胃排空速率(GE)而变化。本项研究的目的是确定基线GE率是否与吸入效率(AE)的差异相关。

背景及目的
吸入治疗(AT)对肥胖的有效性依赖于餐后的最佳抽吸时间,其可以根据患者的排空速率(GE)而变化。本项研究的目的是确定基线GE率是否与吸入效率(AE)的差异相关。

方法
研究人员将AE计算为在20和40分钟时吸入的绝对残余和卡路里。然后将参与者按基线GE率分为两组(慢速与快速)。Wilcoxon秩和检验用于比较组间20和40分钟的AE。线性回归用于评估GE和AE之间的关系。

结果
共有7名患者(85%女性)参与了该研究。平均年龄和体重指数分别为39.8±9.44岁和43±5。AE在整个组的20和40分钟时间点之间没有显着差异(34.3% VS 36.9%; p> 0.5)。然而,那些患有快速GE的人比那些缓慢GE的人吸入更多的卡路里(20分钟:200千卡 VS 72.5千卡; 40分钟:154千卡 VS 63千卡)(p = 0.05)。在线性回归中,延迟的GE与较差的吸入有关。

结论
接受AT治疗的患者可以从加速GE中获益。

原始出处:

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    2019-10-22 gaoxiaoe
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    2019-12-23 贵阳
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    2019-09-13 CHANGE

    疗效只是效果的众多方面之一,还要看对患者的获益,包括生活质量等因素共同决定效果的

    0

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