J Periodontal Res:牙周炎和超重患者唾液、龈沟液及血清中ghrelin和chemerin水平

2017-12-06 MedSci MedSci原创

这项研究旨在量化两种分子(ghrelin和chemerin)的释放与食物摄入量和肥胖相关性,在牙周健康和患病个体方面不同的体重类别。

这项研究旨在量化两种分子(ghrelin和chemerin)的释放与食物摄入量和肥胖相关性,在牙周健康和患病个体方面不同的体重类别。材料与方法:将两个主要分组(慢性牙周炎和牙周健康/牙龈炎志愿者)分为亚组,正常体重[体重指数(BMI)<25]和超重/肥胖组(BMI≥25)组。分析龈下菌群,测定唾液,龈沟液和血清中酰化和总ghrelin,chemerin和白细胞介素-1β(IL-1β)水平。结果:BMI≥25的慢性牙周炎患者组和牙周健康/牙龈炎患者组Treponema denticola总量明显高于BMI <25组。龈沟液中ghrelin总量差异有统计学意义,慢性牙周炎和BMI≥25亚组最低。慢性牙周炎组龈沟液中chemerin水平显着高于BMI <25的牙周健康/牙龈炎患者。然而,龈沟液的IL-1β水平组间区分度最大,BMI <25的慢性牙周炎患者中水平最高和BMI <25的牙周健康/牙龈炎组水平最低。唾液中的chemerin或酰化的ghrelin或外周血清中的酰化的和总的ghrelin的各组之间没有显着差异。 BMI与血清chemerin水平相关。结论:

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    2018-02-03 feather89
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    2017-12-07 飛歌

    学习的

    0

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    2017-12-06 135****7952平儿

    学了......

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    2017-12-06 1ddf0692m34(暂无匿称)

    学习了.好文章

    0

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