Obstet Gynecol:子宫破裂病例产妇肥胖与母婴结局之间有啥关系?

2017-03-25 xing.T MedSci原创

在子宫破裂及母亲肥胖的情况下,会适度增加低Apgar评分、新生儿重症监护病房入住率、延长辅助通气和癫痫发作的风险。 然而,产妇并发症的风险和新生儿死亡的风险与正常BMI患者相似。

近日妇产科权威杂志Obstetrics and Gynecology上发表了一研究文章,研究人员旨在描述在母体肥胖患者中,不良结局风险与子宫破裂之间的相关性。

该研究是对妊娠34-42周子宫破裂后出生的单胎正常新生儿进行的回顾性队列分析。研究人员所用数据来自于2011年至2014年期间美国出生率数据库。孕妇妊娠前体重指数(BMI)按世界卫生组织规定进行分类。并对每个BMI类别计算新生儿和母亲并发症的发生率。研究人员使用多变量logistic回归分析来估计肥胖妊娠与正常妊娠相比的并发症风险。

在2011年至2014年间,共有15860954例(0.02%)孕妇分娩,其中3942例发生子宫破裂。子宫破裂的孕妇中有2917例(74%)符合分析纳入标准。与正常体重孕妇相比,肥胖孕妇发生新生儿较低5分钟Apgar 评分(22.9% vs. 15.9%;调整比值比[OR]为1.49 [1.19-1.87])、新生儿重症监护室入住率(31% vs. 24.6%;调整后的OR为1.51 [1.23-1.85])和癫痫发作(3.7% vs. 1.9%;调整OR为1.80 [1.05-3.10])的风险升高。调整混杂因素后,延长的辅助通气发生率为8.5%,相比于未6.2%(P=0.13),差异具有显著的统计学意义(调整后的OR为1.47 [1.05-2.07])。新生儿死亡率两组相似(12.4 vs. 6.5/1000名婴儿;调整后的OR为2.03 [0.81-5.05])。各组间产妇并发症发生率相似。

在子宫破裂及母亲肥胖的情况下,会适度增加低Apgar评分、新生儿重症监护病房入住率、延长辅助通气和癫痫发作的风险。 然而,产妇并发症的风险和新生儿死亡的风险与正常BMI患者相似。

原始出处:

Yao, Ruofan, et al. Association of Maternal Obesity With Maternal and Neonatal Outcomes in Cases of Uterine Rupture.Obstetrics & Gynecology.2017. http://journals.lww.com/greenjournal/Abstract/2017/04000/Association_of_Maternal_Obesity_With_Maternal_and.13.aspx

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time=2017-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=182714, encodeId=b9a8182e144f, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Sun Mar 26 00:22:01 CST 2017, time=2017-03-26, status=1, ipAttribution=)]
    2017-03-27 zhouqu_8
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time=2017-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=182714, encodeId=b9a8182e144f, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Sun Mar 26 00:22:01 CST 2017, time=2017-03-26, status=1, ipAttribution=)]
    2017-03-26 shaosai

    好好学习,涨知识

    0

  7. 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time=2017-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=182714, encodeId=b9a8182e144f, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Sun Mar 26 00:22:01 CST 2017, time=2017-03-26, status=1, ipAttribution=)]
    2017-03-26 明月清辉

    谢谢分享,学习了

    0

  8. 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time=2017-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=182714, encodeId=b9a8182e144f, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Sun Mar 26 00:22:01 CST 2017, time=2017-03-26, status=1, ipAttribution=)]
    2017-03-26 刘煜

    学习新知识谢谢分享

    0

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time=2017-03-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=182714, encodeId=b9a8182e144f, content=学习一下很不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/11/23/ac01daf0962458a9eb8c0b1e2f6ce5bc.jpg, createdBy=04b81710322, createdName=1771ae4158m, createdTime=Sun Mar 26 00:22:01 CST 2017, time=2017-03-26, status=1, ipAttribution=)]
    2017-03-26 飛歌

    學習了很有用

    0

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    2017-03-26 1771ae4158m

    学习一下很不错

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