lapatinib以及trastuzumab组合可以11天内消灭特定乳腺癌

2016-03-15 佚名 生物谷

利用两种药物组合治疗,能够在11天内抑制或者消灭特定类型的乳腺癌。 相关结果发表在于阿姆斯特丹召开的“欧洲乳腺癌会议上”。这些结果表明:对于一些女性来说,新的治疗方法能够代替目前使用的常规化学疗法。 该药物组合能够靶向HER2蛋白,带蛋白在乳腺癌细胞中出现的几率为10%。HER2阳性的乳腺癌具有恶化程度高以及耐药性强的特点。 该方法的优点在于,它可以起到完全消除肿瘤细胞的作用,而且从诊断到

利用两种药物组合治疗,能够在11天内抑制或者消灭特定类型的乳腺癌。

相关结果发表在于阿姆斯特丹召开的“欧洲乳腺癌会议上”。这些结果表明:对于一些女性来说,新的治疗方法能够代替目前使用的常规化学疗法。

该药物组合能够靶向HER2蛋白,带蛋白在乳腺癌细胞中出现的几率为10%HER2阳性的乳腺癌具有恶化程度高以及耐药性强的特点。

该方法的优点在于,它可以起到完全消除肿瘤细胞的作用,而且从诊断到手术结束之间的间隔很短。

该项试验中, 研究者们招募了257名被确诊为HER2阳性的乳腺癌,而且大小为1-3cm之间的女性患者。其中66名采用了两类药物组合治疗的方法,在不到两周内,11%的患者体内的肿瘤完全消除,另外有17%的患者体内的肿瘤大小减小到5mm以下。

“我们希望这一新型疗法能够成为HER2阳性乳腺癌个体化医疗的里程碑事件”,来自Breast Cancer Care的首席执行官Delyth Morgan说道。

这两类药物分别是lapatinib以及trastuzumab(即Herceptin)。这两类药物目前已知能够特异性针对HER2蛋白。一般情况下,常规的针对HER2阳性乳腺癌的治疗手段需要包括手术,之后再进行化学治疗。然而,Herceptin能够与癌细胞表面相结合,而lapatinib能够穿透细胞从而在内部进行杀伤。

在我们将这一方案向患者推广之前,需要经过更多的试验验证,而且需要检验这一方法对患者的长期效果,其中主要包括HER2阳性癌细胞复发的风险。然而,医学界对这一新开发的治疗方案则表现出浓厚的兴趣与充分的信任。

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    2016-11-10 snf701207
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    2016-06-14 bsmagic9140
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    2016-06-06 LSJ122
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    2016-03-23 jetleo

    需要检验这一方法对患者的长期效果,其中主要包括HER2阳性癌细胞复发的风险。

    0

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