JAHA:心电图提示左室肥大的高血压患者预后明显更差

2017-11-21 MedSci MedSci原创

高血压患者伴有左室肥大(LVH)心电图表现的心源性死亡率和发病率均更高,但是单一的心电图诊断标准可能会低估了心血管风险。本研究纳入了9193名随机分配至氯沙坦或阿替洛尔治疗组的高血压患者,通过康奈尔法和/或Sokolow‐Lyon法对患者左室肥大心电图进行诊断,在4.8±0.9年的随访时间里,对患者的卒中、心梗、心源性死亡、复合结局和全因死亡率与患者心电图的关系进行评估。研究开始时,将患者根据每个

高血压伴有左室肥大(LVH)患者其(LVH)心源性死亡率和发病率均更高,但是单一的心电图诊断标准可能会低估了患者的心血管风险。

本研究纳入了9193名随机分配至氯沙坦或阿替洛尔治疗组的高血压患者,通过康奈尔法和/或Sokolow‐Lyon法对患者左室肥大心电图进行诊断,在4.8±0.9年的随访时间里,对患者的卒中、心梗、心源性死亡、复合结局和全因死亡率与患者心电图的关系进行评估。研究开始时,将患者根据每个心电图左室肥大标准分成4组,两个标准都诊断为左室肥大的患者为960例(10.4%)。与心电图没有左室肥大的患者相比,两个诊断标准都诊断为左室肥大患者发生上述不良心血管事件的风险要增高3倍以上,被一个标准(康奈尔法或Sokolow‐Lyon法)诊断为心电图左室肥大的患者风险要高45%-140%。

研究结果显示,接受抗高血压治疗的高血压患者若被两个标准诊断为心电图左室肥大,则不良心血管事件发生风险要明显增高。

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    2017-11-23 zhaohui6731
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