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J Hypertens：二手烟暴露与非吸烟者心血管危险因素有何关系？

2017-06-07 xing.T MedSci原创

SHSE心血管危险因素
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尽管SHSE与心血管疾病的发病率和死亡率风险增加相关，在这个横断面研究中研究人员没有发现SHSE与血压、血脂或空腹血糖水平之间存在相关性。利用尿液中可替宁客观测量并没有改变这种相关性。需要进一步的长期的前瞻性研究来探讨SHSE作为心血管疾病危险因素的影响。

非吸烟者二手烟暴露（SHSE）已被证实与心血管死亡以及缺血性心脏病相关。近日，高血压领域权威杂志Journal of Hypertension上发表了一篇研究文章，研究人员进行了一项横断面、以人口为基础的研究，旨在评价通过主观和客观的方法进行测量的SHSE与传统的心血管风险，如血压、血脂、空腹血糖之间的关系。

研究人员提取了7376名从不吸烟的健康成年人的信息，这些参与者尿液中可替宁水平的数据可用，并且来自于2008年-2011年期间韩国国家健康和营养调查。SHSE是通过使用自我报告的问卷调查和尿液中可替宁水平来确定。该研究的主要结局包括SBP和DBP、血脂谱和空腹血糖。

研究人群的平均年龄为45.4±0.4岁，女性为75.2%。自我报告的SHSE与除DBP外的研究结局没有显著相关性，DBP也只是勉强呈正相关性（P=0.060）。未经调整的分析显示较高的可替宁水平与较低的SBP、总胆固醇、低密度脂蛋白胆固醇和甘油三酯相关。所有关联在多元调整后失去统计学意义。空腹血糖与尿液中可替宁正相关，但与可替宁对数变换无关。

尽管SHSE与心血管疾病的发病率和死亡率风险增加相关，在这个横断面研究中研究人员没有发现SHSE与血压、血脂或空腹血糖水平之间存在相关性。利用尿液中可替宁客观测量并没有改变这种相关性。需要进一步的长期的前瞻性研究来探讨SHSE作为心血管疾病危险因素的影响。

原始出处：

Kim, Sehun;et al. Relation between secondhand smoke exposure and cardiovascular risk factors in never smokers.Journal of Hypertension. 2017. http://journals.lww.com/jhypertension/Abstract/publishahead/Relation_between_secondhand_smoke_exposure_and.97705.aspx

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    2018-02-12 xinmeili

    #血管危险因素#

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    2017-09-19 feather89

    #PE#

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    2017-06-16 12498ebem19暂无昵称

    #TENS#

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  4. 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createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Tue Jun 13 11:31:03 CST 2017, time=2017-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209866, encodeId=45e120986624, content=好文章学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Mon Jun 12 15:01:01 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331474, encodeId=3a9313314e418, content=<a href='/topic/show?id=afab51e831d' target=_blank style='color:#2F92EE;'>#心血管危险因素#</a>, 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createdBy=3e0221357465, createdName=lingaifan, createdTime=Fri Jun 09 04:02:00 CST 2017, time=2017-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=208205, encodeId=369320820560, content=好文章学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Thu Jun 08 16:11:49 CST 2017, time=2017-06-08, status=1, ipAttribution=)]
    2017-06-13 139****5926

    好文章学习了

    0

  5. 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createdBy=3e0221357465, createdName=lingaifan, createdTime=Fri Jun 09 04:02:00 CST 2017, time=2017-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=208205, encodeId=369320820560, content=好文章学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Thu Jun 08 16:11:49 CST 2017, time=2017-06-08, status=1, ipAttribution=)]
    2017-06-12 139****5926

    好文章学习了

    0

  6. 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createdBy=3e0221357465, createdName=lingaifan, createdTime=Fri Jun 09 04:02:00 CST 2017, time=2017-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=208205, encodeId=369320820560, content=好文章学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Thu Jun 08 16:11:49 CST 2017, time=2017-06-08, status=1, ipAttribution=)]
    2017-06-09 yuhaisheng_ibp_32061711

    #心血管危险因素#

    0

  7. 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createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Tue Jun 13 11:31:03 CST 2017, time=2017-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209866, encodeId=45e120986624, content=好文章学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Mon Jun 12 15:01:01 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331474, encodeId=3a9313314e418, content=<a href='/topic/show?id=afab51e831d' target=_blank style='color:#2F92EE;'>#心血管危险因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51783, encryptionId=afab51e831d, topicName=心血管危险因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bb182500058, createdName=yuhaisheng_ibp_32061711, createdTime=Fri Jun 09 04:02:00 CST 2017, time=2017-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1340117, encodeId=cca7134011ee8, content=<a href='/topic/show?id=77b0239266a' target=_blank style='color:#2F92EE;'>#二手烟#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23926, encryptionId=77b0239266a, topicName=二手烟)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1dfd2500156, createdName=12498c24m69暂无昵称, createdTime=Fri Jun 09 04:02:00 CST 2017, time=2017-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1605109, encodeId=855516051092a, content=<a href='/topic/show?id=5cba39435fd' target=_blank style='color:#2F92EE;'>#吸烟者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39435, encryptionId=5cba39435fd, topicName=吸烟者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cc8619318136, createdName=124984e7m89暂无昵称, createdTime=Fri Jun 09 04:02:00 CST 2017, time=2017-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1629758, encodeId=d57b1629e587e, content=<a href='/topic/show?id=28c351e80dc' target=_blank style='color:#2F92EE;'>#心血管危险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51780, encryptionId=28c351e80dc, topicName=心血管危险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3e0221357465, createdName=lingaifan, createdTime=Fri Jun 09 04:02:00 CST 2017, time=2017-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=208205, encodeId=369320820560, content=好文章学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Thu Jun 08 16:11:49 CST 2017, time=2017-06-08, status=1, ipAttribution=)]
    2017-06-09 12498c24m69暂无昵称

    #二手烟#

    0

  8. 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GetPortalCommentsPageByObjectIdResponse(id=1605109, encodeId=855516051092a, content=<a href='/topic/show?id=5cba39435fd' target=_blank style='color:#2F92EE;'>#吸烟者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39435, encryptionId=5cba39435fd, topicName=吸烟者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cc8619318136, createdName=124984e7m89暂无昵称, createdTime=Fri Jun 09 04:02:00 CST 2017, time=2017-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1629758, encodeId=d57b1629e587e, content=<a href='/topic/show?id=28c351e80dc' target=_blank style='color:#2F92EE;'>#心血管危险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51780, encryptionId=28c351e80dc, topicName=心血管危险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3e0221357465, createdName=lingaifan, createdTime=Fri Jun 09 04:02:00 CST 2017, time=2017-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=208205, encodeId=369320820560, content=好文章学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Thu Jun 08 16:11:49 CST 2017, time=2017-06-08, status=1, ipAttribution=)]
    2017-06-09 124984e7m89暂无昵称

    #吸烟者#

    0

  9. 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createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Tue Jun 13 11:31:03 CST 2017, time=2017-06-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=209866, encodeId=45e120986624, content=好文章学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Mon Jun 12 15:01:01 CST 2017, time=2017-06-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1331474, encodeId=3a9313314e418, content=<a href='/topic/show?id=afab51e831d' target=_blank style='color:#2F92EE;'>#心血管危险因素#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51783, encryptionId=afab51e831d, topicName=心血管危险因素)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bb182500058, createdName=yuhaisheng_ibp_32061711, createdTime=Fri Jun 09 04:02:00 CST 2017, time=2017-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1340117, encodeId=cca7134011ee8, content=<a href='/topic/show?id=77b0239266a' target=_blank style='color:#2F92EE;'>#二手烟#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=42, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23926, encryptionId=77b0239266a, topicName=二手烟)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1dfd2500156, createdName=12498c24m69暂无昵称, createdTime=Fri Jun 09 04:02:00 CST 2017, time=2017-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1605109, encodeId=855516051092a, content=<a href='/topic/show?id=5cba39435fd' target=_blank style='color:#2F92EE;'>#吸烟者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=39435, encryptionId=5cba39435fd, topicName=吸烟者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=cc8619318136, createdName=124984e7m89暂无昵称, createdTime=Fri Jun 09 04:02:00 CST 2017, time=2017-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1629758, encodeId=d57b1629e587e, content=<a href='/topic/show?id=28c351e80dc' target=_blank style='color:#2F92EE;'>#心血管危险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51780, encryptionId=28c351e80dc, topicName=心血管危险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=3e0221357465, createdName=lingaifan, createdTime=Fri Jun 09 04:02:00 CST 2017, time=2017-06-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=208205, encodeId=369320820560, content=好文章学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib06iaV3D9Tg5K1RUfOKQohib4bXhDtxVgOA9VcKY1LUZkCOmr0v3WupxANz2ibibNHkdevtSruvrhyI29IjXdtvUV48/0, createdBy=6ff82057534, createdName=139****5926, createdTime=Thu Jun 08 16:11:49 CST 2017, time=2017-06-08, status=1, ipAttribution=)]
    2017-06-09 lingaifan

    #心血管危险#

    0

  10. 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    2017-06-08 139****5926

    好文章学习了

    0

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