Crit care:ARDS患者进行ECMO的死亡率预测模型比较!

2017-12-17 MedSci MedSci原创

体外膜肺氧合(ECMO)是挽救急性呼吸窘迫综合征(ARDS)患者生命的一种疗法,但其与并发症和花费成本相关。近期,一项发表在杂志Crit care上的研究验证了分数差异对预测死亡率和发展优化的分类模型。此项研究为推导队列研究,对108例静脉-静脉ECMO的ARDS患者(2010-2015)进行了回顾性分析,以评估对死亡率预测(受试者操作)的四个已建立的风险评分(ECMOnet评分,RESP评分,P

体外膜肺氧合(ECMO)是挽救急性呼吸窘迫综合征(ARDS)患者生命的一种疗法,但其与并发症和花费成本相关。近期,一项发表在杂志Crit care上的研究验证了分数差异对预测死亡率和发展优化的分类模型。此项研究为推导队列研究,对108例静脉-静脉ECMO的ARDS患者(2010-2015)进行了回顾性分析,以评估对死亡率预测(受试者操作)的四个已建立的风险评分(ECMOnet评分,RESP评分,PRESERVE评分,Roch评分),并通过多变量逻辑回归分析确定死亡率的自变量,以产生新的PRESET评分(PR生存对ECMO疗法的评分)。然后对这个新的分数进行独立的内部(82例)和外部(59例)队列验证。此项研究结果显示:序贯器官衰竭评估得分的中位数(25%; 75%四分位数)为14(12; 16),简易急性生理学得分II为62.5(57; 72.8),重症监护病房停留中位时间为17天(1-124),死亡率为62%。只有ECMOnet评分(曲线下面积(AUC)0.69)和RESP评分(AUC 0.64)可以区分幸存者和非幸存者。入院pHa、平均动脉压、乳酸、血小板浓度和前ECMO住院时间是

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    2018-07-30 zhangbaojun
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    2018-08-07 drwjr
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    2017-12-22 llaq

    预测模型

    0

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    2017-12-19 I see you

    新理念

    0

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    2017-12-17 1ddf0692m34(暂无匿称)

    学习了.好文章

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    2017-12-17 圣艮山

    学习了不少事情!!

    0

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